{"created":"2023-05-15T16:49:24.577723+00:00","id":26854,"links":{},"metadata":{"_buckets":{"deposit":"5b5659be-b45b-4509-a8f2-bc4bbbee17e7"},"_deposit":{"created_by":6,"id":"26854","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"26854"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00026854","sets":["8:9"]},"author_link":["119119","119120","119117","119115","119116","119118","119122","119121","119123"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-06-18","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageStart":"631","bibliographicVolumeNumber":"57","bibliographic_titles":[{"bibliographic_title":"Medicina"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background and Objectives: Urinary levels of dickkopf-3 (DKK-3) are associated with poor renal survival in patients with non-dialytic chronic kidney disease. However, it remains unknown whether urinary DKK-3 levels can predict residual renal function (RRF) decline in patients undergoing peritoneal dialysis (PD). Therefore, we investigated the correlation between urinary levels of DKK-3 and the subsequent rate of RRF decline in PD patients. Materials and Methods: This study included 36 PD patients who underwent multiple peritoneal equivalent tests during 2011–2021. The relationship between baseline clinical characteristics and the subsequent annual rate of Kt/V decline was investigated. Results: The annual rate of renal Kt/V decline was 0.29 (range: 0.05–0.48), which correlated with renal Kt/V (r = 0.55, p = 0.0005) and 24 h urinary DKK-3 excretion (r = 0.61, p < 0.0001). Similarly, 24 h urinary DKK-3 excretion (β = 0.44, p = 0.0015) and renal Kt/V (β = 0.38, p = 0.0059) were independently associated with the annual rate of renal Kt/V decline in multivariate analyses. Conclusions: Urinary DKK-3 assessment may help identify PD patients at a high risk of RRF decline.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Medicina (Lithuania), 57(6), art. no. 631；2021","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/medicina57060631","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"1648-9144","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Torigoe, Kenta"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Muta, Kumiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tsuji, Kiyokazu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamashita, Ayuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Torigoe, Miki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Abe, Shinichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ota, Yuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mukae, Hiroshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishino, Tomoya"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-11-12"}],"displaytype":"detail","filename":"Medicina57_631.pdf","filesize":[{"value":"508.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Medicina57_631.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/26854/files/Medicina57_631.pdf"},"version_id":"a3280a9d-0ca3-440e-86f9-ca777777f544"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"biomarker","subitem_subject_scheme":"Other"},{"subitem_subject":"Dickkopf-3","subitem_subject_scheme":"Other"},{"subitem_subject":"peritoneal dialysis","subitem_subject_scheme":"Other"},{"subitem_subject":"residual renal function","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Association of Urinary Dickkopf-3 with Residual Renal Function Decline in Patients Undergoing Peritoneal Dialysis","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Association of Urinary Dickkopf-3 with Residual Renal Function Decline in Patients Undergoing Peritoneal Dialysis"}]},"item_type_id":"2","owner":"6","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-11-12"},"publish_date":"2021-11-12","publish_status":"0","recid":"26854","relation_version_is_last":true,"title":["Association of Urinary Dickkopf-3 with Residual Renal Function Decline in Patients Undergoing Peritoneal Dialysis"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T20:09:07.836287+00:00"}