@article{oai:nagasaki-u.repo.nii.ac.jp:00026905,
 author = {Ohnita, Ken and Higashi, Shuntaro and Hirai, Satoshi and Kuwahara, Ai and Kakigao, Kana and Nakashiki, Suguru and Inoue, Kenichiro and Kurohama, Hirokazu and Nakashima, Masahiro and Nakao, Kazuhiko},
 journal = {BMC Gastroenterology},
 month = {Sep},
 note = {Background:  Esophageal metastasis of renal cell carcinoma (RCC) is extremely rare. We have described herein a case of a 59-year-old man with esophageal metastasis of RCC that was endoscopically resected.
Case presentation:  The case was a 59-year-old man who had undergone left nephrectomy for renal clear cell carcinoma 17 years ago and splenectomy for splenic metastasis 3 years ago. Esophagogastroduodenoscopy (EGD) performed 9 years ago revealed a small reddish elevated lesion with a smooth surface in the middle esophagus; this lesion increased in size 4 years ago. However, no biopsy was performed. The lesion continued to grow in size and was found to have become nodular during the present observation. Biopsy revealed clear cell carcinoma. Endoscopic ultrasound (EUS) revealed that the lesion had not invaded the submucosa, and contrast-enhanced computed tomog-raphy did not reveal any other metastasis. The lesion was successfully removed en bloc via endoscopic submucosal dissection (ESD). Pathologically, the tumor was detected in the subepithelium with focal infiltration of the muscularis mucosa. It consisted of monotonous cells with small nuclei and a clear cytoplasm. Immunohistological findings indi-cated that the tumor was a metastasis of RCC. The lateral and vertical margins were noted to be free.
Conclusions:  We have presented herein a case of esophageal metastasis of RCC that had progressed over 9 years and was then resected en bloc through endoscopic submucosal dissection., BMC Gastroenterology, 21, art. no. 348; 2021},
 title = {Esophageal metastasis of renal cell carcinoma resected by endoscopic submucosal dissection: a case report},
 volume = {21},
 year = {2021}
}