{"created":"2023-05-15T16:49:28.493750+00:00","id":26945,"links":{},"metadata":{"_buckets":{"deposit":"c7ef7ecd-fe31-4167-8563-6ad8caaaa7ac"},"_deposit":{"created_by":6,"id":"26945","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"26945"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00026945","sets":["35:36"]},"author_link":["119935","119930","119926","119925","119936","119932","119928","119937","119933","119927","119929","119934","119939","119931","119938"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-10-21","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"art. no. 110","bibliographicVolumeNumber":"20","bibliographic_titles":[{"bibliographic_title":"Environmental Health"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: The differential effects of PM2.5 fractions on children’s lung function remain inconclusive. This study aimed to examine whether lung function in asthmatic children was associated with increased PM2.5 fractions in urban areas in Nagasaki prefecture, Japan, where the air pollution level is relatively low but influenced by transboundary air pollution.\nMethods: We conducted a multiyear panel study of 73 asthmatic children (boys, 60.3%; mean age, 8.2 years) spanning spring 2014–2016 in two cities. We collected self-measured peak expiratory flow (PEF) twice a day and daily time-series data for PM2.5 total mass and its chemical species. We fitted a linear mixed effects model to examine short-term associations between PEF and PM2.5, adjusting for individual and time-varying confounders. A generalized linear mixed effects model was also used to estimate the association for worsening asthma defined by severe PEF decline. Back-trajectory and cluster analyses were used to investigate the long-range transboundary PM2.5 in the study areas.\nResults: We found that morning PEFs were adversely associated with higher levels of sulfate (− 1.61 L/min; 95% CI: − 3.07, − 0.15) in Nagasaki city and organic carbon (OC) (− 1.02 L/min; 95% CI: − 1.94, − 0.09) in Isahaya city, per interquartile range (IQR) increase at lag1. In addition, we observed consistent findings for worsening asthma, with higher odds of severe PEF decline in the morning for sulfate (odds ratio (OR) = 2.31; 95% CI: 1.12, 4.77) and ammonium (OR = 1.73; 95% CI: 1.06, 2.84) in Nagasaki city and OC (OR = 1.51; 95% CI: 1.06, 2.15) in Isahaya city, per IQR increase at lag1. The significant chemical species were higher on days that could be largely attributed to the path of Northeast China origin (for sulfate and ammonium) or both the same path and local sources (for OC) than by other clusters.\nConclusions: This study provides evidence of the differential effects of PM2.5 fractions on lung function among asthmatic children in urban areas, where the Japanese national standards of air quality have been nearly met. Continuous efforts to promote mitigation actions and public awareness of hazardous transboundary air pollution are needed to protect susceptible children with asthma.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Environmental Health, 20, art. no. 110; 2021","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central Ltd"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/s12940-021-00796-x","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1476-069X","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kim, Yoonhee"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Park, Eun Ha"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ng, Chris Fook Sheng"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Chung, Yeonseung"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hashimoto, Kunio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tashiro, Kasumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hasunuma, Hideki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Doi, Masataka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tamura, Kei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Moriuchi, Hiroyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishiwaki, Yuji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kim, Hwajin"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yi, Seung-Muk"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kim, Ho"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hashizume, Masahiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-12-21"}],"displaytype":"detail","filename":"EnvironHealth20_110.pdf","filesize":[{"value":"2.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"EnvironHealth20_110.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/26945/files/EnvironHealth20_110.pdf"},"version_id":"e4a44ba7-3bec-413e-9acb-fc0ca558be5a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Particulate matter","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemical composition","subitem_subject_scheme":"Other"},{"subitem_subject":"Asthma","subitem_subject_scheme":"Other"},{"subitem_subject":"Lung function","subitem_subject_scheme":"Other"},{"subitem_subject":"Children","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Respiratory function declines in children with asthma associated with chemical species of fine particulate matter (PM2.5) in Nagasaki, Japan","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Respiratory function declines in children with asthma associated with chemical species of fine particulate matter (PM2.5) in Nagasaki, Japan"}]},"item_type_id":"2","owner":"6","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-12-21"},"publish_date":"2021-12-21","publish_status":"0","recid":"26945","relation_version_is_last":true,"title":["Respiratory function declines in children with asthma associated with chemical species of fine particulate matter (PM2.5) in Nagasaki, Japan"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T20:05:20.915222+00:00"}