{"created":"2023-05-15T16:49:34.157135+00:00","id":27077,"links":{},"metadata":{"_buckets":{"deposit":"9602e03a-13a9-485b-af3c-da016e80d9f0"},"_deposit":{"created_by":6,"id":"27077","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"27077"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00027077","sets":["35:36"]},"author_link":["120712","120714","120715","120709","120707","120713","120717","120710","120708","120716","120711","120718"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-01-04","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"99","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"Microorganisms"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"In the initial phase of the novel coronavirus disease (COVID-19) pandemic, a large-scale cluster on the cruise ship Diamond Princess (DP) emerged in Japan. Genetic analysis of the DP strains has provided important information for elucidating the possible transmission process of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on a cruise ship. However, genome-based analyses of SARS-CoV-2 detected in large-scale cruise ship clusters other than the DP cluster have rarely been reported. In the present study, whole-genome sequences of 94 SARS-CoV-2 strains detected in the second large cruise ship cluster, which emerged on the Costa Atlantica (CA) in Japan, were characterized to understand the evolution of the virus in a crowded and confined place. Phylogenetic and haplotype network analysis indicated that the CA strains were derived from a common ancestral strain introduced on the CA cruise ship and spread in a superspreading event-like manner, resulting in several mutations that might have affected viral characteristics, including the P681H substitution in the spike protein. Moreover, there were significant genetic distances between CA strains and other strains isolated in different environments, such as cities under lockdown. These results provide new insights into the unique evolution patterns of SARS-CoV-2 in the CA cruise ship cluster.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Microorganisms, 10(1), art. no. 99; 2022","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/microorganisms10010099","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2076-2607","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Abe, Haruka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ushijima, Yuri"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Amano, Murasaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakurai, Yasuteru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshikawa, Rokusuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kinoshita, Takaaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kurosaki, Yohei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yanagihara, Katsunori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Izumikawa, Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Morita, Kouichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kohno, Shigeru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yasuda, Jiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-09"}],"displaytype":"detail","filename":"Microorganisms10_99.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Microorganisms10_99.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/27077/files/Microorganisms10_99.pdf"},"version_id":"6a3e61b0-9fae-4bf8-87cb-beee99e38439"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"SARS-CoV-2","subitem_subject_scheme":"Other"},{"subitem_subject":"evolution","subitem_subject_scheme":"Other"},{"subitem_subject":"phylogeny","subitem_subject_scheme":"Other"},{"subitem_subject":"cruise ship","subitem_subject_scheme":"Other"},{"subitem_subject":"Costa Atlantica","subitem_subject_scheme":"Other"},{"subitem_subject":"Japan","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Unique Evolution of SARS-CoV-2 in the Second Large Cruise Ship Cluster in Japan","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Unique Evolution of SARS-CoV-2 in the Second Large Cruise Ship Cluster in Japan"}]},"item_type_id":"2","owner":"6","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-09"},"publish_date":"2022-02-09","publish_status":"0","recid":"27077","relation_version_is_last":true,"title":["Unique Evolution of SARS-CoV-2 in the Second Large Cruise Ship Cluster in Japan"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T20:00:34.995993+00:00"}