{"created":"2023-05-15T16:49:35.881666+00:00","id":27114,"links":{},"metadata":{"_buckets":{"deposit":"9e072085-9283-4da2-bffc-f6082bf5f4bb"},"_deposit":{"created_by":6,"id":"27114","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"27114"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00027114","sets":["29:30:1713167819629:2019"]},"author_link":["120818","120813","120814","120812","120817","120816","120811","120815"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"36","bibliographicPageStart":"29","bibliographicVolumeNumber":"65","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose: Olfactory deficit has been studied in aging, amnestic mild cognitive impairment (aMCI), Alzheimer’s disease (AD). Parkinson's disease (PD), dementia with Lewy bodies (DLB) and idiopathic REM-sleep behavior disorder (iRBD). Our aim was to investigate the usefulness of a simple test kit “The Odor Stick Identification test for the Japanese ”(OSIT-J) in clinical practice.\nMethods: A total of 240 patients were enrolled in this study, including 44 cognitively normal subjects (NS), 31 patients with aMCI, 70 patients with mild AD (AD-mild), 28 patients with DLB, 31 patients with PD and 36 patients with iRBD. The OSIT-J consists of 12 types of odor sticks. The subjects were asked to select an odor from a list of 4 odors that were rubbed on the medicine wraping paper for each odor stick. The maximum score was 12.\nResults: The mean odor identification (OI) score decreased in the order of aMCI, iRBD, AD-mild, PD and DLB (NS: aMCI, P<0.05, NS: AD-mild, DLB, PD and iRBD, P<0.001, aMCI: DLB, P<0.001, aMCI: PD, P<0.01 (Kruskal-Wallis, Dunn’s test). The sensitivity and specificity in differentiating each disease from NS at a cutoff value of 8 was 96.8% and 79.5%, respectively, in PD, and 96.4% and 79.5% in DLB. An ageing effect was observed in NSs ( r=-0.453 (p<0.01)).\nConclusions: Olfactory deficit is a non-specific phenomenon. However, it is important to be aware of the underlying diseases or future development of diseases. The OSIT-J, which is a simple test, is useful for detecting OI abnormalities in daily clinical practice.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia, 65(2), pp.29-36; 2022","subitem_description_type":"Other"}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagasaki University School of Medicine"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"01"}]},"item_3_text_63":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"長崎大学医学部"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yokogi, Maiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kusano, Kayoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsubara, Rie"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Maki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tomita, Itsuro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Seto, Makiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Satoh, Akira"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tsujihata, Mitsuhiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-02-25"}],"displaytype":"detail","filename":"ActMed65_29.pdf","filesize":[{"value":"672.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ActMed65_29.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/27114/files/ActMed65_29.pdf"},"version_id":"0e5f01a6-e18e-40d4-a3ad-cd4a6910b616"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Odor identification","subitem_subject_scheme":"Other"},{"subitem_subject":"OSIT-J","subitem_subject_scheme":"Other"},{"subitem_subject":"Alzheimer's disease","subitem_subject_scheme":"Other"},{"subitem_subject":"Dementia with Lewy bodies","subitem_subject_scheme":"Other"},{"subitem_subject":"amnestic mild cognitive impairment","subitem_subject_scheme":"Other"},{"subitem_subject":"REM sleep behavior disorder","subitem_subject_scheme":"Other"},{"subitem_subject":"Parkinson's disease","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases"}]},"item_type_id":"3","owner":"6","path":["2019"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-02-25"},"publish_date":"2022-02-25","publish_status":"0","recid":"27114","relation_version_is_last":true,"title":["Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2024-04-18T01:20:41.407617+00:00"}