@article{oai:nagasaki-u.repo.nii.ac.jp:00027146,
 author = {Tobías, Aurelio and Hashizume, Masahiro and Honda, Yasushi and Sera, Francesco and Ng, Chris Fook Sheng and Kim, Yoonhee and Roye, Dominic and Chung, Yeonseung and Dang, Tran Ngoc and Kim, Ho and Lee, Whanhee and Íñiguez, Carmen and Vicedo-Cabrera, Ana and Abrutzky, Rosana and Guo, Yuming and Tong, Shilu and Coelho, Micheline de Sousa Zanotti Stagliorio and Saldiva, Paulo Hilario Nascimento and Lavigne, Eric and Correa, Patricia Matus and Ortega, Nicolás Valdés and Kan, Haidong and Osorio, Samuel and Kyselý, Jan and Urban, Aleš and Orru, Hans and Indermitte, Ene and Jaakkola, Jouni J. K. and Ryti, Niilo R. I. and Pascal, Mathilde and Huber, Veronika and Schneider, Alexandra and Katsouyanni, Klea and Analitis, Antonis and Entezari, Alireza and Mayvaneh, Fatemeh and Goodman, Patrick and Zeka, Ariana and Michelozzi, Paola and de’Donato, Francesca and Alahmad, Barrak and Diaz, Magali Hurtado and De la Cruz Valencia, César and Overcenco, Ala and Houthuijs, Danny and Ameling, Caroline and Rao, Shilpa and Di Ruscio, Francesco and Carrasco, Gabriel and Seposo, Xerxes and Nunes, Baltazar and Madureira, Joana and Holobaca, Iulian-Horia and Scovronick, Noah and Acquaotta, Fiorella and Forsberg, Bertil and Åström, Christofer and Ragettli, Martina S. and Guo, Yue-Liang Leon and Chen, Bing-Yu and Li, Shanshan and Colistro, Valentina and Zanobetti, Antonella and Schwartz, Joel and Dung, Do Van and Armstrong, Ben and Gasparrini, Antonio},
 issue = {5},
 journal = {Environmental Epidemiology},
 month = {Sep},
 note = {Background: Minimum mortality temperature (MMT) is an important indicator to assess the temperature-mortality association, indicating long-term adaptation to local climate. Limited evidence about the geographical variability of the MMT is available at a global scale.
Methods: We collected data from 658 communities in 43 countries under different climates. We estimated temperature-mortality associations to derive the MMT for each community using Poisson regression with distributed lag nonlinear models. We investigated the variation in MMT by climatic zone using a mixed-effects meta-analysis and explored the association with climatic and socioeconomic indicators.
Results: The geographical distribution of MMTs varied considerably by country between 14.2 and 31.1 °C decreasing by latitude. For climatic zones, the MMTs increased from alpine (13.0 °C) to continental (19.3 °C), temperate (21.7 °C), arid (24.5 °C), and tropical (26.5 °C). The MMT percentiles (MMTPs) corresponding to the MMTs decreased from temperate (79.5th) to continental (75.4th), arid (68.0th), tropical (58.5th), and alpine (41.4th). The MMTs indreased by 0.8 °C for a 1 °C rise in a community’s annual mean temperature, and by 1 °C for a 1 °C rise in its SD. While the MMTP decreased by 0.3 centile points for a 1 °C rise in a community’s annual mean temperature and by 1.3 for a 1 °C rise in its SD.
Conclusions: The geographical distribution of the MMTs and MMTPs is driven mainly by the mean annual temperature, which seems to be a valuable indicator of overall adaptation across populations. Our results suggest that populations have adapted to the average temperature, although there is still more room for adaptation., Environmental Epidemiology, 5(5), e169; 2021},
 title = {Geographical Variations of the Minimum Mortality Temperature at a Global Scale},
 volume = {5},
 year = {2021}
}