{"created":"2023-05-15T16:31:20.025568+00:00","id":2719,"links":{},"metadata":{"_buckets":{"deposit":"48d2a440-7133-40df-a957-8dabd8135ac2"},"_deposit":{"created_by":2,"id":"2719","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"2719"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00002719","sets":["10:11"]},"author_link":["12495","12489","12490","12491","12488","12487","12494","12492","12496","12493"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-11-21","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"77","bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"Environmental Health and Preventive Medicine"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Triglycerides are reported to be positively associated with blood pressure (both systolic and diastolic). However, in a previous study, we reported a significant positive association between triglycerides and circulating CD34-positive cells (endothelial repair) among non-hypertensive, but not hypertensive, participants. Since hypertension and endothelial dysfunction have a bi-directional association (vicious cycle), the status of circulating CD34-positive cells may influence the association between triglycerides and hypertension. Methods: Since antihypertensive medication use may influence results of the present study, we conducted a cross-sectional study of 327 community dwelling elderly (aged 60-69 years) Japanese participants who were not taking anti-hypertensive medication and who had participated in a general health check-up in 2013-2015. Results: Participants were classified into two groups based on median values of circulating CD34-positive cells (0.93 cells/μL). For participants with lower circulating CD34-positive cells (n = 165), a significant positive association was seen between triglycerides and blood pressure, but not for participants with higher circulating CD34-positive cells (n = 162). The multivariable standardized parameter estimates (β) and p values of systolic blood pressure and diastolic blood pressure were 0.23 (p = 0.007) and 0.18 (p = 0.036) for participants with lower circulating CD34-positive cells and 0.08 (p = 0.409) and 0.03 (p = 0.786) for those with higher circulating CD34-positive cells. Conclusion: A significant positive association between triglycerides and blood pressure exists among those with lower, but not higher, circulating CD34-positive cells. The level of circulating CD34-positive cells acts as a determinant factor for the association between triglycerides and blood pressure.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Environmental Health and Preventive Medicine, 22, 77; 2017","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central Ltd."}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/s12199-017-0684-x","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1342078X","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13474715","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shimizu, Yuji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Shimpei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Noguchi, Yuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Koyamatsu, Jun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamanashi, Hirotomo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagayoshi, Mako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kadota, Koichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawashiri, Shin-Ya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagata, Yasuhiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Takahiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"EHPM22_77.pdf","filesize":[{"value":"570.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"EHPM22_77.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/2719/files/EHPM22_77.pdf"},"version_id":"d09619ef-46fa-4ef6-8fa4-15f955a167a7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"CD34-positive cell","subitem_subject_scheme":"Other"},{"subitem_subject":"Hypertension","subitem_subject_scheme":"Other"},{"subitem_subject":"Triglycerides","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Triglycerides and blood pressure in relation to circulating CD34-positive cell levels among community-dwelling elderly Japanese men: a cross-sectional study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Triglycerides and blood pressure in relation to circulating CD34-positive cell levels among community-dwelling elderly Japanese men: a cross-sectional study"}]},"item_type_id":"2","owner":"2","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-01-29"},"publish_date":"2018-01-29","publish_status":"0","recid":"2719","relation_version_is_last":true,"title":["Triglycerides and blood pressure in relation to circulating CD34-positive cell levels among community-dwelling elderly Japanese men: a cross-sectional study"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:42:12.602164+00:00"}