{"created":"2023-05-15T16:31:20.068129+00:00","id":2720,"links":{},"metadata":{"_buckets":{"deposit":"1167f8fa-d5c2-43f6-a4df-119d083f8f6e"},"_deposit":{"created_by":2,"id":"2720","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"2720"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00002720","sets":["35:36"]},"author_link":["12508","12509","12502","12497","12501","12498","12506","12511","12505","12500","12504","12499","12507","12510","12503"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-11-22","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"627","bibliographicPageStart":"621","bibliographicVolumeNumber":"70","bibliographic_titles":[{"bibliographic_title":"Japanese Journal of Infectious Diseases"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We studied the prevalence of HIV drug resistance among high-risk groups such as injecting drug users (IDUs), female sex workers (FSWs), and men having sex with men (MSM) in central Vietnam. We used HIV-positive blood samples from 2012?2013 sentinel surveillance surveys. Study subjects were screened for HIV infection by standardized screening assays, and the HIV-positive samples were further tested for HIV viral load and drug-resistance mutations (DRMs) by in-house assays. DRMs were identified using the Stanford University online sequence analysis tool. Their risk behaviors were also investigated. During the study period, 6,016 (high-risk) subjects were screened, and 97 tested positive for HIV infection (IDUs: n = 63, 3.0%; FSWs: n = 24, 0.9%; and MSM: n = 10, 1.0%). Ninety-two of the 97 samples (45 from 2012 and 47 from 2013) were available for further testing. HIV RNA was detected in 56 (60.9%) of the 92 samples, and drug resistance genotyping was successfully performed on 40 (71.4%) samples. All these isolates were subtype CRF01_AE, except for 1 (2.5%) IDU whose HIV belongs to subtype B. Thirteen individuals (32.5%) were carrying HIV with at least 1 DRM: 9 IDUs, 1 FSW, and 3 MSM. Thus, HIV seroprevalence among high-risk individuals in central Vietnam is low, but a high proportion of drug resistant HIV-1 isolates is observed in the high-risk group.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Japanese Journal of Infectious Diseases, 70(6), pp.621-627; 2017","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"国立感染症研究所"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.7883/yoken.JJID.2016.512","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2017 National Institute of Infectious Diseases"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13446304","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"18842836","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"National Institute of Infectious Diseases"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Do, Hung Thai"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nguyen, Dong Thanh"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nguyen, Lan Anh Thi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Do, Duong Huy"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Le, Huy Xuan"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Trinh, Xuan Mai Thi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ton, Hong Vy Nu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sawada, Ikumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitamura, Noriko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Le, Minh Nhat"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshihara, Keisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Phan, Thu Huong Thi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Bui, Chien Trong"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ariyoshi, Koya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshida, Lay Myint"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"JID70_621.pdf","filesize":[{"value":"380.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JID70_621.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/2720/files/JID70_621.pdf"},"version_id":"53bae4b9-15da-4e5c-b2ff-c08a35a4889d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"human immunodeficiency virus (HIV)","subitem_subject_scheme":"Other"},{"subitem_subject":"high-risk group","subitem_subject_scheme":"Other"},{"subitem_subject":"risk behavior","subitem_subject_scheme":"Other"},{"subitem_subject":"antiretroviral drug resistance","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"An Alarmingly High Proportion of HIV-1 Isolates Carrying Mutations Corresponding to Resistance to Antiretroviral Drugs among HIV-Positive High-Risk Groups in Central Vietnam: a Substudy of the National Sentinel Survey","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"An Alarmingly High Proportion of HIV-1 Isolates Carrying Mutations Corresponding to Resistance to Antiretroviral Drugs among HIV-Positive High-Risk Groups in Central Vietnam: a Substudy of the National Sentinel Survey"}]},"item_type_id":"2","owner":"2","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-01-30"},"publish_date":"2018-01-30","publish_status":"0","recid":"2720","relation_version_is_last":true,"title":["An Alarmingly High Proportion of HIV-1 Isolates Carrying Mutations Corresponding to Resistance to Antiretroviral Drugs among HIV-Positive High-Risk Groups in Central Vietnam: a Substudy of the National Sentinel Survey"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:42:10.449149+00:00"}