{"created":"2023-05-15T16:49:41.641984+00:00","id":27249,"links":{},"metadata":{"_buckets":{"deposit":"a838c11e-4751-411c-bc8f-86bd8d3ded88"},"_deposit":{"created_by":6,"id":"27249","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"27249"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00027249","sets":["8:9"]},"author_link":["121494","121495","121492","121496","121493"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-03-28","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageStart":"223","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"Toxins"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A percutaneous renal biopsy is an essential tool for the diagnosis of various renal diseases;however, post-biopsy bleeding is a major complication. Hemocoagulase is a detoxified and purified snake venom enzyme that is widely used to prevent post-procedural bleeding. In this study, we retrospectively analyzed the effect of hemocoagulase on post-renal biopsy bleeding. We included 221 patients who underwent percutaneous renal biopsy between April 2017 and December 2020 and analyzed post-renal biopsy hemoglobin (Hb) decline in patients who were administered a periprocedural hemocoagulase injection. After the renal biopsy, the mean Hb decrease in the entire patient cohort was 0.33 ・ 0.84 g/dL. Periprocedural hemocoagulase injection lowered the Hb decline post-renal biopsy (0.50 ・ 0.87 vs. 0.23 ・ 0.80 g/dL, p = 0.0204). The propensity-matched cohort was also adjusted for factors influencing postprocedural bleeding; periprocedural hemocoagulase injection reduced the Hb decline post-renal biopsy (0.56 ・ 0.89 vs. 0.17 ・ 0.74 g/dL, p = 0.006). There were no adverse events (e.g., thrombosis and anaphylactic shock) due to hemocoagulase. Our study demonstrated the beneficial effect of hemocoagulase on post-renal biopsy Hb decline, suggesting its clinical value in preventing post-renal biopsy bleeding.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Toxins, 14(3), art.no.223; 2022","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/toxins14030223","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"©2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/)"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Torigoe, Kenta"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamashita, Ayuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Abe, Shinichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Muta, Kumiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishino, Tomoya"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-04-18"}],"displaytype":"detail","filename":"Toxins14-223.pdf","filesize":[{"value":"929.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Toxins14-223.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/27249/files/Toxins14-223.pdf"},"version_id":"17cd73cf-43ff-439e-a19a-2b6b45553daf"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"renal biopsy","subitem_subject_scheme":"Other"},{"subitem_subject":"complication","subitem_subject_scheme":"Other"},{"subitem_subject":"hemocoagulase","subitem_subject_scheme":"Other"},{"subitem_subject":"post-procedural bleeding","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effect of Hemocoagulase on the Prevention of Bleeding after Percutaneous Renal Biopsy","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effect of Hemocoagulase on the Prevention of Bleeding after Percutaneous Renal Biopsy"}]},"item_type_id":"2","owner":"6","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-04-18"},"publish_date":"2022-04-18","publish_status":"0","recid":"27249","relation_version_is_last":true,"title":["Effect of Hemocoagulase on the Prevention of Bleeding after Percutaneous Renal Biopsy"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T19:52:48.240766+00:00"}