{"created":"2023-05-15T16:49:57.830025+00:00","id":27633,"links":{},"metadata":{"_buckets":{"deposit":"e3ce6881-3eef-465b-a506-bf07b8b74f40"},"_deposit":{"created_by":6,"id":"27633","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"27633"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00027633","sets":["10:11"]},"author_link":["122825","122828","122830","122831","122824","122829","122823","122826","122832","122822","122827"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-09-17","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"771","bibliographicVolumeNumber":"22","bibliographic_titles":[{"bibliographic_title":"BMC Pregnancy and Childbirth"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Breastfeeding in the early postpartum period is expected to have mental benefits for mothers; however, the underlying sychobiological mechanisms remain unclear. Previously, we hypothesized that the release of oxytocin in response to the suckling stimuli during breastfeeding would mediate a calming effect on primiparous mothers, and we examined salivary oxytocin measurements in primiparous mothers at postpartum day 4 using saliva samples without extraction, which was erroneous. Thus, further confirmation of this hypothesis with a precise methodology was needed.\nMethods: We collected saliva samples at three time points (baseline, feeding, and post-feeding) to measure oxytocin in 24 primiparous mothers on postpartum day 2 (PD2) and 4 (PD4) across the breastfeeding cycle. Salivary oxytocin levels using both extracted and unextracted methods were measured and compared to determine the qualitative differences. State and trait anxiety and clinical demographics were evaluated to determine their association with oxytocin changes.\nResults: Breastfeeding elevated salivary oxytocin levels; however, it was not detected to a significant increase in the extraction method at PD4. We found a weak but significant positive correlation between changes in extracted and unextracted oxytocin levels during breastfeeding (feeding minus baseline); there were no other significant positive correlations. Therefore, we used the extracted measurement index for subsequent analysis. We showed that the greater the increase in oxytocin during breastfeeding, the lower the state anxiety, but not trait anxiety. Mothers who exclusively breastfed at the 1-month follow-up tended to be associated with slightly higher oxytocin change at PD2 than those who did not.\nConclusions: Breastfeeding in early postpartum days could be accompanied by the frequent release of oxytocin and lower state anxiety, potentially contributing to exclusive breastfeeding.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"BMC Pregnancy and Childbirth, 22 (1), art. no. 711; 2022　","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central Ltd"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/s12884-022-05026-x","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© The Author(s) 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativeco mmons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1471-2393","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nagahashi-Araki, Miyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tasaka, Makoto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takamura, Tsunehiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Eto, Hiromi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sasaki, Noriko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujita, Wakako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyazaki, Asuka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Morifuji, Kanako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Honda, Naoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyamura, Tunetake"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishitani, Shota"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-10-06"}],"displaytype":"detail","filename":"BMCPC22_711.pdf","filesize":[{"value":"2.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"BMCPC22_711.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/27633/files/BMCPC22_711.pdf"},"version_id":"b4630b70-b244-4c42-93c9-9cb0fd4802e7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Anxiety","subitem_subject_scheme":"Other"},{"subitem_subject":"Calming effect","subitem_subject_scheme":"Other"},{"subitem_subject":"Extraction","subitem_subject_scheme":"Other"},{"subitem_subject":"Maternity blues","subitem_subject_scheme":"Other"},{"subitem_subject":"Postpartum depression","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Endogenous oxytocin levels in extracted saliva elevates during breastfeeding correlated with lower postpartum anxiety in primiparous mothers","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Endogenous oxytocin levels in extracted saliva elevates during breastfeeding correlated with lower postpartum anxiety in primiparous mothers"}]},"item_type_id":"2","owner":"6","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-10-06"},"publish_date":"2022-10-06","publish_status":"0","recid":"27633","relation_version_is_last":true,"title":["Endogenous oxytocin levels in extracted saliva elevates during breastfeeding correlated with lower postpartum anxiety in primiparous mothers"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T19:35:49.706592+00:00"}