{"created":"2023-05-15T16:50:05.622771+00:00","id":27811,"links":{},"metadata":{"_buckets":{"deposit":"8ae2c544-d602-4289-8fce-062e006cf988"},"_deposit":{"created_by":6,"id":"27811","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"27811"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00027811","sets":["10:11"]},"author_link":["123792","123793","123789","123794","123791","123790"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-12-18","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"24","bibliographicPageStart":"9025","bibliographicVolumeNumber":"27","bibliographic_titles":[{"bibliographic_title":"Molecules"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Glycerol is the main side product in the biodiesel manufacturing process, and the development of glycerol valorization methods would indirectly contribute the sustainable biodiesel production and decarbonization. Transformation of glycerol to optically active C3 units would be one of the attractive routes for glycerol valorization. We herein present the asymmetric sulfonylative desymmetrization of glycerol by using a CuCN/(R,R)-PhBOX catalyst system to provide an optically active monosulfonylated glycerol in high efficiency. A high degree of enantioselectivity was achieved with a commercially available chiral ligand and an inexpensive carbonate base. The optically active monosulfonylated glycerol was successfully transformed into a C3 unit attached with differentially protected three hydroxy moieties. In addition, the synthetic utility of the present reaction was also demonstrated by the transformation of the monosulfonylated glycerol into an optically active synthetic ceramide, sphingolipid E.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":" Molecules, 27(24), art. no. 9025; 2022","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/molecules27249025","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1420-3049","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yamamoto, Kosuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyamoto, Keisuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ueno, Mizuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takemoto, Yuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kuriyama, Masami"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Onomura, Osamu"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-01-05"}],"displaytype":"detail","filename":"M27_9025.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"M27_9025.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/27811/files/M27_9025.pdf"},"version_id":"9e9b1603-7f6b-4725-87e1-a8c82b04f35c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"copper catalysis","subitem_subject_scheme":"Other"},{"subitem_subject":"asymmetric reaction","subitem_subject_scheme":"Other"},{"subitem_subject":"desymmetrization","subitem_subject_scheme":"Other"},{"subitem_subject":"glycerol","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Copper-Catalyzed Asymmetric Sulfonylative Desymmetrization of Glycerol","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Copper-Catalyzed Asymmetric Sulfonylative Desymmetrization of Glycerol"}]},"item_type_id":"2","owner":"6","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-01-05"},"publish_date":"2023-01-05","publish_status":"0","recid":"27811","relation_version_is_last":true,"title":["Copper-Catalyzed Asymmetric Sulfonylative Desymmetrization of Glycerol"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T18:21:34.319657+00:00"}