{"created":"2023-05-15T16:50:06.437102+00:00","id":27830,"links":{},"metadata":{"_buckets":{"deposit":"a6677427-f1ee-4b9f-b5b4-1d0c153ee64b"},"_deposit":{"created_by":6,"id":"27830","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"27830"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00027830","sets":["8:9"]},"author_link":["123938","123939","123940","123943","123944","123937","123945","123942","123936","123941"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-12-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"606","bibliographicPageStart":"600","bibliographicVolumeNumber":"20","bibliographic_titles":[{"bibliographic_title":"Lymphatic Research and Biology"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Lymphedema may develop when axillary lymph node dissection (ALND) injures and obstructs the lymph ducts in the upper limb. In patients with breast cancer, lymphedema is difficult to treat and can cause arm swelling, heaviness, and restricted movement. We aimed to identify the prevalence and risk factors for lymphedema after ALND in patients with breast cancer.\nMethods and Results: This retrospective study included 175 patients with breast cancer who underwent ALND in the Nagasaki University Hospital, Japan, between 2005 and 2018. Lymphedema was defined as symptomatic arm swelling with a >2-cm difference in the arm circumference between the affected and contralateral arms. Patients were divided into two groups according to the presence or absence of lymphedema. Surgical and pathological findings were compared between the two groups. Univariate and multivariate analyses were performed, including the chi-square test, Student’s t-test, and logistic regression analysis. Lymphedema was prevalent in 20% of the study participants, and the mean time interval from surgery to development of lymphedema was 479 days. In the univariate analysis, a body mass index of >26 kg/m2, smoking, radiotherapy (RT), and dissection of >18 axillary lymph nodes (ALNs) significantly increased the risk of lymphedema. In the multivariate analysis, smoking, RT, and dissection of >18 ALNs significantly increased the risk of lymphedema.\nConclusions: The prevalence of lymphedema in our study was 20%. Our findings suggest that smoking, RT, and dissection of >18 ALNs are risk factors for lymphedema. Aggressive and empiric ALND might be associated with axillary lymph duct damage.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Lymphatic research and biology, 20(6), pp.600-606; 2022　","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Mary Ann Liebert, Inc"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1089/lrb.2021.0033","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"ⓒ Yuki Hara et al. 2022; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the CreativeCommons  Attribution  Noncommercial  License  [CC-BY-NC]  (http://creativecommons.org/licenses/by-nc/4.0/)  which  permits  any  non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and the source are cited."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1539-6851","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hara, Yuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Otsubo, Ryota"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shinohara, Shota"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Morita, Michi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kuba, Sayaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsumoto, Megumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamanouchi, Kosho"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yano, Hiroshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Eguchi, Susumu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagayasu, Takeshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-01-13"}],"displaytype":"detail","filename":"LRB20_600.pdf","filesize":[{"value":"208.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"LRB20_600.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/27830/files/LRB20_600.pdf"},"version_id":"f9dc01d9-4670-4b00-a6ec-f21bb7de0507"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"axillary lymph node dissection","subitem_subject_scheme":"Other"},{"subitem_subject":"axillary reverse mapping","subitem_subject_scheme":"Other"},{"subitem_subject":"breast cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"lymphedema","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Lymphedema After Axillary Lymph Node Dissection in Breast Cancer: Prevalence and Risk Factors—A Single-Center Retrospective Study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Lymphedema After Axillary Lymph Node Dissection in Breast Cancer: Prevalence and Risk Factors—A Single-Center Retrospective Study"}]},"item_type_id":"2","owner":"6","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-01-13"},"publish_date":"2023-01-13","publish_status":"0","recid":"27830","relation_version_is_last":true,"title":["Lymphedema After Axillary Lymph Node Dissection in Breast Cancer: Prevalence and Risk Factors—A Single-Center Retrospective Study"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T18:17:19.847384+00:00"}