@article{oai:nagasaki-u.repo.nii.ac.jp:00027864, author = {Dila, Kadek Agus Surya and Reda, Ahmed and Elhady, Mohamed Tamer and Linh, Le Khac and Minh-Duc, Nguyen Tran and El-Qushayri, Amr Ehab and Han, Nguyen Lac and Mehta, Varshil and Hamad, Walid Mohamed Attiah and Eskarous, Hany and Samsom, Maryan and Hirayama, Kenji and Huy, Nguyen Tien}, journal = {Acta Tropica}, month = {Nov}, note = {A chronic helminth infection can alter host immune response and affect malaria infection. We conducted a systematic review and meta-analysis to find the impact of anthelmintic treatment on malaria prevalence, incidence, and parasitemia. Nine and 12 electronic databases were searched on 28th July 2015 and 26th June 2020 for relevant studies. We performed meta-analysis for malaria prevalence, incidence, parasitemia, and a qualitative synthesis for other effects of anthelmintic treatment. Seventeen relevant papers were included. There was no association between anthelmintic treatment and malaria prevalence or change of parasitemia at the end of follow up period (pooled OR 0.93, 95% CI: 0.62, 1.38, p-value=0.71 and SMD -0.08, 95%CI: -0.24, 0.07, p-value=0.30 respectively) or at any defined time points in analysis. Pooled analysis of three studies demonstrated no association between malaria incidence and anthelmintic treatment (rate ratio 0.93, 95%CI: 0.80, 1.08, p-value=0.33). Our study encourages anthelmintic treatment in countries with high burden of co-infections as anthelmintic treatment is not associated with change in malaria prevalence, incidence, or parasitemia., Acta Tropica, 225, art. no. 106213; 2021}, title = {Association of anthelmintic treatment with malaria prevalence, incidence, and parasitemia: A systematic review and meta-analysis}, volume = {225}, year = {2021} }