@phdthesis{oai:nagasaki-u.repo.nii.ac.jp:00027998,
 author = {松村, 佑介},
 month = {Mar},
 note = {BACKGROUND: The presence of depressive symptoms in patients with non-tuberculous mycobacterial pulmonary disease (NTM-PD) is an important research topic; however, the prevalence of depressive symptoms and the factors that influence their development are unclear. 
OBJECTIVE: To analyse the association between CES-D (Center for Epidemiological Studies Depression Scale) scores and clinical parameters such as age, disease duration, pulmonary function, imaging findings, blood data, physical functions, sleep disturbances, respiratory symptoms and health-related quality of life (HRQOL). 
METHODS: We conducted a cross-sectional retrospective study of 114 patients with NTM-PD at a single centre from March 2016 to January 2021 to evaluate the relationship between CES-D scores and clinical parameters. 
RESULTS: Participants had a median age of 64 years; 32.5% of them had depressive symptoms. Disease duration, albumin, C-reactive protein, pulmonary function, dyspnoea, exercise capacity, respiratory symptoms, cough-related HRQOL and sleep disturbances were associated with depressive symptoms. Binomial logistic regression analyses indicated that the CES-D score was significantly associated with cough-related HRQOL and sleep disturbances. 
CONCLUSION: A high percentage of NTM-PD patients in this study experienced depressive symptoms, and these patients had abnormalities of various clinical parameters. Cough-related HRQOL and sleep disturbance had a strong influence on the development of depressive symptoms., 長崎大学学位論文 学位記番号:博(医歯薬)甲第1490号 学位授与年月日:令和5年3月20日, Author: Matsumura, Y. ; Tabusadani, M. ; Yamane, K. ; Takao, S. ; Kuroyama, Y. ; Mori, K. ; Ono, K. ; Kawahara, K. ; Omatsu, S. ; Furuuchi, K. ; Fujiwara, K. ; Morimoto, K. ; Kimura, H. ; Senjyu, H, Citation: The International Journal of Tuberculosis and Lung Disease, 26(4), pp. 310-316; 2022, Nagasaki University (長崎大学), 博士(医学) (2023-03-20)},
 school = {Nagasaki University (長崎大学)},
 title = {Prevalence of and risk factors for depressive symptoms in non-tuberculous mycobacterial pulmonary disease},
 year = {2023}
}