{"created":"2023-05-15T16:50:24.190582+00:00","id":28244,"links":{},"metadata":{"_buckets":{"deposit":"de64a2f2-6703-4f4b-a986-02db547d4c7f"},"_deposit":{"created_by":6,"id":"28244","owners":[6],"pid":{"revision_id":0,"type":"depid","value":"28244"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00028244","sets":["10:11"]},"author_link":["125636","125633","125637","125638","125639","125642","125641","125630","125644","125631","125635","125643","125634","125632","125640"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-03-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageStart":"e012432","bibliographicVolumeNumber":"67","bibliographic_titles":[{"bibliographic_title":"Antimicrobial Agents and Chemotherapy"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Candida auris is resistant to multiple antifungal agents. This study investigated its antifungal susceptibility and explored FKS1 mutations across the isolates from mice enterically colonized with wild-type C. auris and treated with echinocandin. Resistant C. auris with FKS1 mutations, including S639F, S639Y, D642Y, R1354H, or R1354Y, were isolated and found to be micafungin- and caspofungin-resistant in vivo; however, the MICs of isolates with mutation in R1354 remained below the micafungin breakpoint in vitro.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Antimicrobial agents and chemotherapy, 67(4), art. no. e0124322; 2023　","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"American Society for Microbiology"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1128/aac.01243-22","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2023 American Society forMicrobiology. Antimicrobial agents and chemotherapy, 67(4), art. no. e0124322; 2023."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0066-4804","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hirayama, Tatsuro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Miyazaki, Taiga"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sumiyoshi, Makoto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ito, Yuya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ashizawa, Nobuyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeda, Kazuaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Iwanaga, Naoki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takazono, Takahiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamamoto, Kazuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Izumikawa, Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yanagihara, Katsunori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Makimura, Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tsukamoto, Kazuhiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kohno, Shigeru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mukae, Hiroshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-05-01"}],"displaytype":"detail","filename":"AAC67_e012432.pdf","filesize":[{"value":"341.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AAC67_e012432.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/28244/files/AAC67_e012432.pdf"},"version_id":"29f9639d-60e7-45d1-81a8-e3ee9bf5b242"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Candida auris","subitem_subject_scheme":"Other"},{"subitem_subject":"yeast","subitem_subject_scheme":"Other"},{"subitem_subject":"antifungal resistance","subitem_subject_scheme":"Other"},{"subitem_subject":"gastrointestinal tract","subitem_subject_scheme":"Other"},{"subitem_subject":"FKS1","subitem_subject_scheme":"Other"},{"subitem_subject":"echinocandins","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 Mutations","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 Mutations"}]},"item_type_id":"2","owner":"6","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2023-05-01"},"publish_date":"2023-05-01","publish_status":"0","recid":"28244","relation_version_is_last":true,"title":["Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 Mutations"],"weko_creator_id":"6","weko_shared_id":-1},"updated":"2023-05-15T17:58:52.542623+00:00"}