@article{oai:nagasaki-u.repo.nii.ac.jp:00000306,
 author = {Meng, Xiangyue and Yamanouchi, Kosho and Kuba, Sayaka and Sakimura, Chika and Morita, Michi and Matsuguma, Kunihito and Kanetaka, Kengo and Takatsuki, Mitsuhisa and Abe, Kuniko and Eguchi, Susumu},
 journal = {International Journal of Surgery Case Reports},
 month = {Sep},
 note = {Introduction: Fibroadenomas are common benign lesions of the breast that are usually found young patients. Giant fibroadenomas are uncommon benign lesions, defined as fibroadenomas of >5 cm in size, which are usually found in patients of less than 20 years of age. Presentation of case: A 39-year-old premenopausal woman presented with a right breast tumor that had rapidly increased in size and which showed ulceration and bleeding. Needle biopsy showed mixed connective tissue and an epithelial tumor without a leaf-like pattern, but indeterminate. Total mastectomy and skin grafting were performed. Histopathology confirmed the diagnosis of giant fibroadenoma. Discussion: In comparison to all previous reports on patients with giant fibroadenoma, this patient was relatively old and the etiology was unknown. Although rare, an appropriate therapeutic strategy should be decided according to the results of a histopathological examination. Conclusion: Early treatment could allow breast preserving surgery and patients should be recommended to undergo reexamination with awareness of progression., International Journal of Surgery Case Reports, 63, pp.36-39; 2019},
 pages = {36--39},
 title = {Giant fibroadenoma of the breast: A rare case in a mature woman},
 volume = {63},
 year = {2019}
}