{"created":"2023-05-15T16:29:19.912098+00:00","id":33,"links":{},"metadata":{"_buckets":{"deposit":"bfb4113b-8c78-44fc-ba78-9a29212c428d"},"_deposit":{"created_by":2,"id":"33","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"33"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00000033","sets":["12:13"]},"author_link":["231","225","227","232","229","230","228","226","233"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020-08-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageStart":"e0008473","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"PLOS Neglected Tropical Diseases"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Despite growing evidence that infants and very young children can be infected with schistosomes, the epidemiological \nfeatures and risk factors are not well described in this age group. We aimed to assess the prevalence of S. mansoni \ninfection in children under two years of age from a population with a known high burden of infection in school-aged children and adults and thus inform the need for interventions in this potentially vulnerable age group. In a cross-sectional study in Mbita Sub-county, along the east coast of Lake Victoria, Western Kenya, we enrolled \n361 children aged 6-23 months. The prevalence of S. mansoni infection was detected using the Kato-Katz stool \nexamination and a point-of-care test for urinary circulating cathodic antigen (POC-CCA) (Rapid Medical Diagnostics, Pretoria, South Africa). Three-hundred and five (305) children had complete data of whom 276 (90.5%, 95%CI: 86.6-93.5)children were positive for S. mansoni by the POC-CCA test, while 11 (3.6%, 95%CI: 1.8-6.4) were positive by the Kato-Katz method. All Kato-Katz positive cases were also positive by the POC-CCA test. In multivariable analysis, \nonly geographical area, Rusinga West (AOR = 7.1, 95%CI: 1.4-35.2, P = 0.02), was associated with S. mansoni infection \nusing Kato-Katz test. Independent associations for POC-CCA positivity included age, (12-17 months vs 6-11 months;AOR = 7.8, 95%CI: 1.8-32.6, P = 0.002) and breastfeeding in the previous 24 hours (AOR = 3.4, 95%CI: 1.3-9.0, P = 0.009). We found a potentially very high prevalence of S. mansoni infection among children under two years of age based on POC-CCA test results in Mbita Sub-county, Kenya, which if confirmed strongly supports the need \nto include infants in public health strategies providing universal prophylactic treatment in high burden settings.Further research is required to determine the accuracy of diagnostic tools to detect light infection among very young children and possible long-term health impacts.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"PLoS neglected tropical diseases, 14(8), e0008473; 2020","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Public Library of Science"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1371/journal.pntd.0008473","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2020 Sassa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited."}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"19352735","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sassa, Miho"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Chadeka, Evans A."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Cheruiyot, Ngetich B."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanaka, Mio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Moriyasu, Taeko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kaneko, Satoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Njenga, Sammy M."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Cox, Sharon E."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hamano, Shinjiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-16"}],"displaytype":"detail","filename":"PLoSNeg14_8473o.pdf","filesize":[{"value":"1.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PLoSNeg14_8473o.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/33/files/PLoSNeg14_8473o.pdf"},"version_id":"7286c633-e43b-496a-9c96-c3c1604baeb0"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Prevalence and risk factors of Schistosoma mansoni infection among children under two years of age in Mbita, Western Kenya","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Prevalence and risk factors of Schistosoma mansoni infection among children under two years of age in Mbita, Western Kenya"}]},"item_type_id":"2","owner":"2","path":["13"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-09-11"},"publish_date":"2020-09-11","publish_status":"0","recid":"33","relation_version_is_last":true,"title":["Prevalence and risk factors of Schistosoma mansoni infection among children under two years of age in Mbita, Western Kenya"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T04:22:12.971447+00:00"}