@article{oai:nagasaki-u.repo.nii.ac.jp:00003408,
 author = {Yamada, Shin-ichi and Hayashida, Saki and Yanamoto, Souichi and Naruse, Tomofumi and Matsusita, Yuki and Uda, Akiko and Rokutanda, Satoshi and Kakehashi, Hiroe and Ikeda, Hisazumi and Asahina, Izumi and Umeda, Masahiro},
 issue = {3},
 journal = {Acta medica Nagasakiensia},
 month = {Apr},
 note = {Bisphosphonates (BPs) are now widely used to treat various skeletal complications. Although the number of reported cases of
bisphosphonate-related osteonecrosis of the jaw (BRONJ) is rapidly increasing worldwide, therapeutic strategies remain controversial.
Conservative treatments including antibacterial mouth rinses, the systemic administration of antibiotics, and superficial debridement in stage II BRONJ have been recommended by the American Association of Oral and Maxillofacial Surgeons position paper. However, these treatments are only partially successful. We performed a surgical intervention that consisted of osteotomy and primary wound closure in patients with stages II and III BRONJ. Forty-three out of 44 cases were treated effectively by this strategy, leading to improvements in quality of life. All BRONJ patients treated with oral BPs were treated successfully by the surgical intervention. We also proposed a surgical intervention for patients with stage II BRONJ., Acta medica Nagasakiensia, 60(3), pp.97-102; 2016},
 pages = {97--102},
 title = {A New Strategy for Surgical Intervention of Bisphosphonate-Related Osteonecrosis of the Jaw : A retrospective study.},
 volume = {60},
 year = {2016}
}