{"created":"2023-05-15T16:29:33.502107+00:00","id":349,"links":{},"metadata":{"_buckets":{"deposit":"adc79c0f-6fcf-4a46-9ace-74c2d5f6a8cf"},"_deposit":{"created_by":2,"id":"349","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"349"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00000349","sets":["25:26"]},"author_link":["1678","1680","1679","1677"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-09-02","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageStart":"1290","bibliographicVolumeNumber":"11","bibliographic_titles":[{"bibliographic_title":"Cancers"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Enormous amounts of childhood thyroid cancers, mostly childhood papillary thyroid\ncarcinomas (PTCs), after the Chernobyl nuclear power plant accident have revealed a mutual relationship between the radiation exposure and thyroid cancer development. While the internal exposure to radioactive 131I is involved in the childhood thyroid cancers after the Chernobyl accident,people exposed to the external radiation, such as atomic-bomb (A-bomb) survivors, and the patients who received radiation therapy, have also been epidemiologically demonstrated to develop thyroid cancers. In order to elucidate the mechanisms of radiation-induced carcinogenesis, studies have aimed at defining the molecular changes associated with the thyroid cancer development. Here,we overview the literatures towards the identification of oncogenic alterations, particularly gene\nrearrangements, and discuss the existence of radiation signatures associated with radiation-induced thyroid cancers.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Cancers, 11(9), art.no.1290; 2019","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/cancers11091290","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/)."}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"20726694","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Suzuki, Keiji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Saenko, Vladimir"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamashita, Shunichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mitsutake, Norisato"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-18"}],"displaytype":"detail","filename":"Cancers11_1290.pdf","filesize":[{"value":"442.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Cancers11_1290.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/349/files/Cancers11_1290.pdf"},"version_id":"ea4ca5fc-68a8-4c5b-9ab5-f191049d44a8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"radiation","subitem_subject_scheme":"Other"},{"subitem_subject":"thyroid carcinoma","subitem_subject_scheme":"Other"},{"subitem_subject":"RET/PTC","subitem_subject_scheme":"Other"},{"subitem_subject":"driver mutation","subitem_subject_scheme":"Other"},{"subitem_subject":"molecular signature","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Radiation-Induced Thyroid Cancers: Overview of Molecular Signatures","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Radiation-Induced Thyroid Cancers: Overview of Molecular Signatures"}]},"item_type_id":"2","owner":"2","path":["26"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-11-01"},"publish_date":"2019-11-01","publish_status":"0","recid":"349","relation_version_is_last":true,"title":["Radiation-Induced Thyroid Cancers: Overview of Molecular Signatures"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T04:18:18.466362+00:00"}