{"created":"2023-05-15T16:32:03.604208+00:00","id":3731,"links":{},"metadata":{"_buckets":{"deposit":"f4f9332b-70e6-4e36-a3df-28f15471a9f6"},"_deposit":{"created_by":2,"id":"3731","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"3731"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00003731","sets":["73:74"]},"author_link":["15201","15203","15202"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-11-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"12","bibliographicPageEnd":"20997","bibliographicPageStart":"20979","bibliographicVolumeNumber":"20","bibliographic_titles":[{"bibliographic_title":"Molecules"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Aptamers have a promising role in the field of life science and have been extensively\nresearched for application as analytical tools, therapeutic agents and as vehicles for targeted drug delivery. Compared with RNA aptamers, DNA aptamers have inherent advantages in stability and facility of generation and synthesis. To better understand the specific potential of DNA aptamers, an overview of the progress in the generation and application of DNA aptamers in human disease diagnosis and therapy are presented in this review. Special attention is given to researches that are relatively close to practical application. DNA aptamers are expected to have great potential in the\ndiagnosis and treatment of human diseases.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Molecules, 20(12), pp.20979-20997; 2015","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Multidisciplinary Digital Publishing Institute (MDPI)"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/molecules201219739","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/)."}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"14203049","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Zhu, Qinchang"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Liu, Ge"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kai, Masaaki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"Mole20_20979.pdf","filesize":[{"value":"818.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Mole20_20979.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/3731/files/Mole20_20979.pdf"},"version_id":"3220035f-c1a0-4a76-ad7d-525968227995"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"DNA aptamers","subitem_subject_scheme":"Other"},{"subitem_subject":"human diseases","subitem_subject_scheme":"Other"},{"subitem_subject":"diagnosis","subitem_subject_scheme":"Other"},{"subitem_subject":"therapeutics","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"DNA Aptamers in the Diagnosis and Treatment of Human Diseases","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"DNA Aptamers in the Diagnosis and Treatment of Human Diseases"}]},"item_type_id":"2","owner":"2","path":["74"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-10-28"},"publish_date":"2016-10-28","publish_status":"0","recid":"3731","relation_version_is_last":true,"title":["DNA Aptamers in the Diagnosis and Treatment of Human Diseases"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:29:33.899267+00:00"}