@article{oai:nagasaki-u.repo.nii.ac.jp:00003736,
 author = {Oba, Makoto and Kato, Takuma and Furukawa, Kaori and Tanaka, Masakazu},
 journal = {Scientific Reports},
 month = {Jan},
 note = {A peptide composed of lysine with a guanidinylethyl (GEt) amine structure in the side chain [Lys(GEt)] was developed as a cell-penetrating peptide directed to plasmid DNA (pDNA) delivery. The GEt amine adopted a diprotonated form at neutral pH, which may have led to the more efficient cellular uptake of a Lys(GEt)-peptide than an arginine-peptide at a low concentration. Lys(GEt)-peptide/pDNA complexes showed the highest transfection efficiency due to efficient endosomal escape without any cytotoxicity. Lys(GEt)-peptide may be a promising candidate as a gene delivery carrier., Scientific Reports, 6, 19913; 2016},
 title = {A Cell-Penetrating Peptide with a Guanidinylethyl Amine Structure Directed to Gene Delivery},
 volume = {6},
 year = {2016}
}