@article{oai:nagasaki-u.repo.nii.ac.jp:00000039, author = {Kuriyama, Masami and Hanazawa, Natsumi and Abe, Yusuke and Katagiri, Kotone and Ono, Shimpei and Yamamoto, Kosuke and Onomura, Osamu}, issue = {31}, journal = {Chemical Science}, month = {Aug}, note = {Metal-free N- and O-arylation reactions of pyridin-2-ones as ambident nucleophiles have been achieved with diaryliodonium salts on the basis of base-dependent chemoselectivity. In the presence of N,N-diethylaniline in fluorobenzene, pyridin-2-ones were very selectively converted to N-arylated products in high yields. On the other hand, the O-arylation reactions smoothly proceeded with the use of quinoline in chlorobenzene, leading to high yields and selectivities. In these methods, a variety of pyridin-2-ones in addition to pyridin-4-one and a set of diaryliodonium salts were accepted as suitable reaction partners., Chemical Science, 11(31), pp.8295-8300; 2020}, pages = {8295--8300}, title = {N- and O-arylation of pyridin-2-ones with diaryliodonium salts: base-dependent orthogonal selectivity under metal-free conditions}, volume = {11}, year = {2020} }