{"created":"2023-05-15T16:29:35.810128+00:00","id":404,"links":{},"metadata":{"_buckets":{"deposit":"b1527aab-49d1-454a-865a-e18b38d9521f"},"_deposit":{"created_by":2,"id":"404","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"404"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00000404","sets":["35:36"]},"author_link":["2110","2111","2104","2096","2107","2100","2105","2097","2102","2101","2108","2106","2103","2099","2109","2098"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-11-21","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"419","bibliographicPageStart":"413","bibliographicVolumeNumber":"72","bibliographic_titles":[{"bibliographic_title":"Japanese Journal of Infectious Diseases"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"engue remains a major public health problem in the Philippines. In this study, we determined the circulating dengue serotypes in the Philippines during the 2015?2017 outbreaks using a total of 678 serum samples from 537 individual dengue patients. Following an increase in the number of DENV-4 patients in recent years, we conducted a comprehensive molecular and epidemiology analysis on the DENV-4 strains isolated recently in the Philippines. Two genotypes of DENV-4 have been isolated in the Philippines since 1956: GI and GIIa. The GIIa DENV strains that were isolated in the present study were closely related to a distinct group of GIIa strains that were isolated from the Philippines in 2004. A majority of the isolates of this sub-group have been identified in the Philippines, suggesting that this lineage may have been introduced in the Philippines, and evolved to form the distinct sub-group within GIIa strains. The increase in DENV-4 activity also coincided with the appearance of the GIIa sub-group and the phasing-out of the GI lineage in the Philippines. Overall, our study demonstrates a shift in DENV-4 genotype and epidemic dynamics in a hyperendemic region, suggesting the importance of DENV genetic evolution in establishing and sustaining transmission.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Japanese Journal of Infectious Diseases, 72(6), pp.413-419; 2019","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"国立感染症研究所"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.7883/yoken.JJID.2019.208","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2019, National Institute of Health."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"13446304","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"18842836","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"National Institute of Health"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Luz, Mark Anthony de Vera"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nabeshima, Takeshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Moi, Meng Ling"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Dimamay, Maria Terrese Alonzo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Pangilinan, Lady-Anne Suarez"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Dimamay, Mark Pierre Sijo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matias, Ronald Roll"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mapua, Cynthia Abad"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Buerano, Corazon Cerilla"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"de, Guzman  Ferdinand"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tria, Edith Sangalang"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Natividad, Filipinas Florendo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Daroy, Maria Luisa de Guzman"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takemura, Taichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hasebe, Futoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Morita, Kouichi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-18"}],"displaytype":"detail","filename":"JJID72_413.pdf","filesize":[{"value":"2.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JJID72_413.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/404/files/JJID72_413.pdf"},"version_id":"3d47ee8e-9d39-4bb7-8eec-a03ae9b63246"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"dengue","subitem_subject_scheme":"Other"},{"subitem_subject":"emergence","subitem_subject_scheme":"Other"},{"subitem_subject":"Philippines","subitem_subject_scheme":"Other"},{"subitem_subject":"serotype","subitem_subject_scheme":"Other"},{"subitem_subject":"genotype","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"An Epidemic of Dengue Virus Serotype-4 during the 2015 - 2017: the Emergence of a Novel Genotype IIa of DENV-4 in the Philippines","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"An Epidemic of Dengue Virus Serotype-4 during the 2015 - 2017: the Emergence of a Novel Genotype IIa of DENV-4 in the Philippines"}]},"item_type_id":"2","owner":"2","path":["36"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-12-05"},"publish_date":"2019-12-05","publish_status":"0","recid":"404","relation_version_is_last":true,"title":["An Epidemic of Dengue Virus Serotype-4 during the 2015 - 2017: the Emergence of a Novel Genotype IIa of DENV-4 in the Philippines"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T04:17:07.966222+00:00"}