{"created":"2023-05-15T16:32:16.575059+00:00","id":4055,"links":{},"metadata":{"_buckets":{"deposit":"37bc2a7f-165b-4787-a2e7-a604077ec9cf"},"_deposit":{"created_by":2,"id":"4055","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"4055"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00004055","sets":["29:30"]},"author_link":["16177","16180","16175","16181","16176","16179","16174","16178"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"367","bibliographicPageStart":"361","bibliographicVolumeNumber":"41","bibliographic_titles":[{"bibliographic_title":"European Journal of Surgical Oncology (EJSO)"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction Patients with muscle-invasive bladder cancer (MIBC) often undergo various preoperative treatments to improve survival; however, their efficacy and safety remain unclear. Materials and methods The anti-tumour effects and adverse events were evaluated in 163 MIBC patients who received systemic chemotherapy (SC, n = 34), intra-arterial chemotherapy (IAC, n = 50), or combined IAC and radiotherapy (IAC + R, n = 79). Results Pathological complete responses were observed in 17.6%, 22.0%, and 43.0% of patients in the SC, IAC, and IAC + R groups, respectively, with respective 5-year overall survival rates of 42.0%, 46.7%, and 50.3%. Multivariate analysis showed that successful IAC + R protocol administration was a significant predictor for survival (hazard ratio = 0.16, p = 0.028). The incidence of severe adverse events was higher in the IAC + R group (36.7%) than in the SC (9.8%) and IAC groups (16.0%). Conclusions IAC + R was useful for patients with MIBC. Successful completion and optimal patient selection were important for this treatment strategy.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"European Journal of Surgical Oncology (EJSO), 41(3), pp.361-367; 2015","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"W.B. Saunders Ltd"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.ejso.2014.07.043","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/)."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"07487983","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Miyata, Yasuyoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nomata, Koichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohba, K."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuo, T."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayashi, N."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakamoto, I."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Uetani, M."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakai, H."}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"EJSO41_361.pdf","filesize":[{"value":"858.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"EJSO41_361.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/4055/files/EJSO41_361.pdf"},"version_id":"4ef497dc-9bf2-40e9-adfc-d761da51f5ae"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Adverse events","subitem_subject_scheme":"Other"},{"subitem_subject":"Bladder cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Chemotherapy","subitem_subject_scheme":"Other"},{"subitem_subject":"Preoperative treatment","subitem_subject_scheme":"Other"},{"subitem_subject":"Prognosis","subitem_subject_scheme":"Other"},{"subitem_subject":"Radiotherapy","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Efficacy and safety of systemic chemotherapy and intra-arterial chemotherapy with/without radiotherapy for bladder preservation or as neo-adjuvant therapy in patients with muscle-invasive bladder cancer: A single-centre study of 163 patients","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Efficacy and safety of systemic chemotherapy and intra-arterial chemotherapy with/without radiotherapy for bladder preservation or as neo-adjuvant therapy in patients with muscle-invasive bladder cancer: A single-centre study of 163 patients"}]},"item_type_id":"2","owner":"2","path":["30"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-03-31"},"publish_date":"2015-03-31","publish_status":"0","recid":"4055","relation_version_is_last":true,"title":["Efficacy and safety of systemic chemotherapy and intra-arterial chemotherapy with/without radiotherapy for bladder preservation or as neo-adjuvant therapy in patients with muscle-invasive bladder cancer: A single-centre study of 163 patients"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:26:28.186259+00:00"}