{"created":"2023-05-15T16:32:18.770840+00:00","id":4107,"links":{},"metadata":{"_buckets":{"deposit":"8dfe65ca-6087-4870-a746-82c395270cff"},"_deposit":{"created_by":2,"id":"4107","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"4107"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00004107","sets":["29:30:1713167819629:277"]},"author_link":["16382","16386","16381","16388","16389","16387","16383","16380","16385","16384"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"97","bibliographicPageStart":"91","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Although our previous study found that diabetes combined with a high serum triglycerides to high-density lipoprotein cholesterol (TG-HDL) ratio constitutes a risk for atherosclerosis and chronic kidney disease (CKD), the association, in terms of TG-HDL ratio, between diabetes and white blood cell (WBC) count, which is an independent risk factor for atherosclerosis, has not been clarified. To investigate this association, we conducted a cross-sectional study of 3,998 Japanese subjects aged 30-89 years undergoing a general health check. We investigated the associations between WBC count and diabetes for all subjects, who were divided into tertiles according to TG-HDL level. Independent of classical cardiovascular risk factors, WBC count of both men and women was positively associated with diabetes combined with high but not with low TG-HDL. The multivariable odds ratios (ORs) and 95% confidence intervals (95%CIs) of 1SD (standard deviation) increment in WBC count (1,538/μL for men, 1,382/μL for women) for high TG-HDL diabetes and low TG-HDL diabetes were 1.39 (95%CI: 1.04-1.85) and 0.88 (95%CI: 0.66-1.19) for men, and 1.83 (95%CI: 1.45-2.33) and 0.91 (95%CI: 0.64-1.29) for women, respectively. In conclusion, for both men and women, WBC count is associated with high TG-HDL diabetes but not with low TG-HDL diabetes. These findings suggest that measuring WBC count is clinically relevant for estimating the risk of atherosclerosis and CKD in patients with diabetes categorized according to TG-HDL ratio.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia, 59(3), pp.91-97; 2015","subitem_description_type":"Other"}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagasaki University School of Medicine"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"3"}]},"item_3_text_63":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"長崎大学医学部"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shimizu, Yuji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakazato, Mio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kadota, Koichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Shimpei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Koyamatsu, Jun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Arima, Kazuhiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamasaki, Hironori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takamura, Noboru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Aoyagi, Kiyoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Takahiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"ActMed59_91.pdf","filesize":[{"value":"501.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ActMed59_91.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/4107/files/ActMed59_91.pdf"},"version_id":"4b0e56c3-98a0-4f4d-8b2b-6eced502801c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"WBC","subitem_subject_scheme":"Other"},{"subitem_subject":"TG-HDL","subitem_subject_scheme":"Other"},{"subitem_subject":"Diabetes","subitem_subject_scheme":"Other"},{"subitem_subject":"Cross-sectional study","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Association between white blood cell count and diabetes in relation to triglycerides-to-HDL cholesterol ratio in a Japanese population: The Nagasaki Islands study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Association between white blood cell count and diabetes in relation to triglycerides-to-HDL cholesterol ratio in a Japanese population: The Nagasaki Islands study"}]},"item_type_id":"3","owner":"2","path":["277"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-04-15"},"publish_date":"2015-04-15","publish_status":"0","recid":"4107","relation_version_is_last":true,"title":["Association between white blood cell count and diabetes in relation to triglycerides-to-HDL cholesterol ratio in a Japanese population: The Nagasaki Islands study"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2024-04-16T05:28:43.292209+00:00"}