@phdthesis{oai:nagasaki-u.repo.nii.ac.jp:00004301,
 author = {宮本, 直美},
 month = {Mar},
 note = {Air pollution in Japan caused respiratory disease, such as chronic bronchitis and asthma, in many individuals in the 1960s. Although air pollution has decreased, many victims of air pollution-related respiratory disease are limited in their activities of daily living because of respiratory symptoms. The purpose of this study was to evaluate the efficacy of pulmonary rehabilitation in victims of air pollution-related chronic bronchitis or asthma. Subjects were enrolled in a 12-week (2-week inpatient followed by 10-week outpatient) pulmonary rehabilitation program. The program comprised conditioning, strength training, endurance training, and patient education. We assessed the Modifed Medical Research Council (MMRC) dyspnea grade, pulmonary function, peripheral muscle force, incremental shuttle walk distance (ISWD), and physical activity at baseline and immediately after the program. Twenty-nine subjects (mean age 74.2 ± 10.1 years, 11 males) completed the program, including 11 subjects with COPD and 18 subjects with asthma. Following rehabilitation, the participants (n = 29) showed signifcant improvements in MMRC dyspnea grade, vital capacity % predicted, quadriceps force and ISWD (all P < 0.05). Sub-group analyses revealed that all these variables were signifcantly improved in subjects with asthma. In contrast, subjects with COPD showed signifcant improvements only in quadriceps force and ISWD (both P < 0.05). Thus, pulmonary rehabilitation is an effective method of improving exercise capacity and dyspnea in officially acknowledged victims of air pollution-related asthma. In conclusion, we recommend that patients with chronic bronchitis or asthma, resulting from exposure to air pollution, are referred for pulmonary rehabilitation., 長崎大学学位論文 学位記番号:博(医歯薬)甲第687号 学位授与年月日:平成26年3月20日, Author: Miyamoto Naomi, Senjyu Hideaki, Tanaka Takako, Asai Masaharu, Yanagita Yorihide, Yano Yudai, Nishinakagawa Tsuyoshi, Kotaki Kenji, Kitagawa Chika, Rikitomi Naoto, Kozu Ryo, Honda Sumihisa, Citation: The Tohoku Journal of Experimental Medicine, 232(1), pp.1-8; 2014, Nagasaki University (長崎大学), 博士(医学) (2014-03-20)},
 school = {Nagasaki University (長崎大学)},
 title = {Pulmonary Rehabilitation Improves Exercise Capacity and Dyspnea in Air Pollution-Related Respiratory Disease},
 year = {2014}
}