@article{oai:nagasaki-u.repo.nii.ac.jp:00000446,
 author = {Satoh, Katsuya and Fuse, Takayuki and Nonaka, Toshiaki and Dong, Trong and Takao, Masaki and Nakagaki, Takehiro and Ishibashi, Daisuke and Taguchi, Yuzuru and Mihara, Ban and Iwasaki, Yasushi and Yoshida, Mari and Nishida, Noriyuki},
 issue = {24},
 journal = {Molecules},
 month = {Dec},
 note = {Human prion diseases are neurodegenerative disorders caused by prion protein. Although infectivity was historically detected only in the central nervous system and lymphoreticular tissues of patients with sporadic Creutzfeldt-Jakob disease, recent reports suggest that the seeding activity of Creutzfeldt-Jakob disease prions accumulates in various non-neuronal organs including the liver, kidney, and skin. Therefore, we reanalyzed autopsy samples collected from patients with sporadic and genetic human prion diseases and found that seeding activity exists in almost all digestive organs. Unexpectedly, activity in the esophagus reached a level of prion seeding activity close to that in the central nervous system in some CJD patients, indicating that the safety of endoscopic examinations should be reconsidered., Molecules, 24(24), art.no.4601; 2019},
 title = {Postmortem Quantitative Analysis of Prion Seeding Activity in the Digestive System},
 volume = {24},
 year = {2019}
}