@article{oai:nagasaki-u.repo.nii.ac.jp:00004646, author = {Tomonaga, Masaomi and Sakamoto, Noriho and Ishimatsu, Yuji and Kakugawa, Tomoyuki and Harada, Tatsuhiko and Nakashima, Shota and Hara, Atsuko and Hara, Shintaro and Horai, Yoshihiro and Kawakami, Atsushi and Mukae, Hiroshi and Kohno, Shigeru}, issue = {1}, journal = {Lung}, month = {Feb}, note = {Anti-PL-7 is an anti-tRNA synthetase antibody, and interstitial lung disease (ILD) is the most frequent complication of anti-PL-7-associated antisynthetase syndrome. However, the features of ILD have not been fully elucidated. The present study retrospectively compares 7 and 15 patients who were positive for anti-PL-7 and anti-Jo-1 antibodies, respectively. The features of ILD did not significantly differ between the two groups, but the ratio of lymphocytes in bronchoalveolar lavage fluid was higher in the Jo-1 than in the PL-7 group. High-resolution computed tomography revealed nonspecific interstitial pneumonia in all patients in the PL-7 group and organizing pneumonia in four of the 15 patients in the Jo-1 group. These findings suggest that pulmonary complications slightly differ between patients expressing anti-PL-7 and anti-Jo-1 antibodies. Further studies are required to clarify the features of ILD associated with PL-7., Lung, 193(1), pp.79-83; 2015}, pages = {79--83}, title = {Comparison of Pulmonary Involvement Between Patients Expressing Anti-PL-7 and Anti-Jo-1 Antibodies}, volume = {193}, year = {2015} }