@article{oai:nagasaki-u.repo.nii.ac.jp:00004691, author = {Yanagihara, Katsunori and Kadota, Junichi and Aoki, Nobuki and Matsumoto, Tetsuya and Yoshida, Masaki and Yagisawa, Morimasa and Oguri, Toyoko and Sato, Junko and Ogasawara, Kazuhiko and Wakamura, Tomotaro and Sunakawa, Keisuke and Watanabe, Akira and Iwata, Satoshi and Kaku, Mitsuo and Hanaki, Hideaki and Ohsaki, Yoshinobu and Watari, Tomohisa and Toyoshima, Eri and Takeuchi, Kenichi and Shiokoshi, Mayumi and Takeda, Hiroaki and Miki, Makoto and Kumagai, Toshio and Nakanowatari, Susumu and Takahashi, Hiroshi and Utagawa, Mutsuko and Nishiya, Hajime and Kawakami, Sayoko and Kobayashi, Nobuyuki and Takasaki, Jin and Mezaki, Kazuhisa and Konosaki, Hisami and Aoki, Yasuko and Yamamoto, Yumiko and Shoji, Michi and Goto, Hajime and Saraya, Takeshi and Kurai, Daisuke and Okazaki, Mitsuhiro and Niki, Yoshihito and Yoshida, Koichiro and Kawana, Akihiko and Saionji, Katsu and Fujikura, Yuji and Miyazawa, Naoki and Kudo, Makoto and Sato, Yoshimi and Yamamoto, Masaki and Yoshida, Takashi and Nakamura, Masahiko and Tsukada, Hiroki and Imai, Yumiko and Tsukada, Ayami and Kawasaki, Satoshi and Honma, Yasuo and Yamamoto, Toshinobu and Ban, Nobuyoshi and Mikamo, Hiroshige and Sawamura, Haruki and Miyara, Takayuki and Toda, Hirofumi and Sato, Kaori and Nakamura, Tadahiro and Fujikawa, Yasunori and Mitsuno, Noriko and Mikasa, Keiichi and Kasahara, Kei and Sano, Reiko and Sugimoto, Keisuke and Asari, Seishi and Nishi, Isao and Toyokawa, Masahiro and Miyashita, Naoyuki and Koguchi, Yutaka and Kusano, Nobuchika and Mihara, Eiichirou and Kuwabara, Masao and Watanabe, Yaeko and Kawasaki, Yuji and Takeda, Kenichi and Tokuyasu, Hirokazu and Masui, Kayoko and Negayama, Kiyoshi and Hiramatsu, Kazufumi and Aoki, Yosuke and Fukuoka, Mami and Magarifuchi, Hiroki and Nagasawa, Zenzo and Suga, Moritaka and Muranaka, Hiroyuki and Morinaga, Yoshitomo and Honda, Junichi and Fujita, Masaki}, issue = {6}, journal = {Journal of Infection and Chemotherapy}, month = {Jun}, note = {The nationwide surveillance on antimicrobial susceptibility of bacterial respiratory pathogens from patients in Japan, was conducted by Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases and Japanese Society for Clinical Microbiology in 2010.The isolates were collected from clinical specimens obtained from well-diagnosed adult patients with respiratory tract infections during the period from January and April 2010 by three societies. Antimicrobial susceptibility testing was conducted at the central reference laboratory according to the method recommended by Clinical and Laboratory Standard Institutes using maximum 45 antibacterial agents.Susceptibility testing was evaluable with 954 strains (206 Staphylococcus aureus, 189 Streptococcus pneumoniae, 4 Streptococcus pyogenes, 182 Haemophilus influenzae, 74 Moraxella catarrhalis, 139 Klebsiella pneumoniae and 160 Pseudomonas aeruginosa). Ratio of methicillin-resistant S.aureus was as high as 50.5%, and those of penicillin-intermediate and -resistant S.pneumoniae were 1.1% and 0.0%, respectively. Among H.influenzae, 17.6% of them were found to be β-lactamase-non-producing ampicillin (ABPC)-intermediately resistant, 33.5% to be β-lactamase-non-producing ABPC-resistant and 11.0% to be β-lactamase-producing ABPC-resistant strains. Extended spectrum β-lactamase-producing K.pneumoniae and multi-drug resistant P.aeruginosa with metallo β-lactamase were 2.9% and 0.6%, respectively.Continuous national surveillance of antimicrobial susceptibility of respiratory pathogens is crucial in order to monitor changing patterns of susceptibility and to be able to update treatment recommendations on a regular basis., Journal of Infection and Chemotherapy, 21(6), pp.410-420; 2015}, pages = {410--420}, title = {Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2010: General view of the pathogens' antibacterial susceptibility}, volume = {21}, year = {2015} }