@article{oai:nagasaki-u.repo.nii.ac.jp:00004907,
 author = {Kamada, Kai and Yamada, Akane and Soh, Nobuaki},
 issue = {104},
 journal = {RSC Advances},
 month = {Oct},
 note = {The effect of the coexistence of titanate nanosheets (TNS) with nanometric lateral dimensions (ca. 3 nm), which were prepared through a hydrolysis reaction of titanium tetraisopropoxide, on the catalytic activity of horseradish peroxidase (HRP) was investigated as a function of solution pH. Especially in diluted HRP solutions with a pH range of 7-8, enzymatic reaction rate, i.e. maximum velocity (Vmax), in the conventional Michaelis-Menten equation, was significantly enhanced more than 2 times in the presence of TNS. In contrast, the increase in Vmax was not very large in acidic (pH = 4.0) and basic solutions (pH = 9.0). It was demonstrated that the TNS brought about peptization of aggregates composed of several HRP molecules in a diluted solution, causing an increase in the apparent HRP concentration participating in the enzymatic reaction. Moreover, the TNS activated superoxide dismutase (SOD) with O2 - scavenging performance., RSC Advances, 5(104), pp.85511-85516; 2015},
 pages = {85511--85516},
 title = {Enhanced catalytic activity of enzymes interacting with nanometric titanate nanosheets},
 volume = {5},
 year = {2015}
}