@article{oai:nagasaki-u.repo.nii.ac.jp:00004934,
 author = {Nakamura, Hideki and Shimizu, Toshimasa and Takagi, Yukinori and Takahashi, Yoshiko and Horai, Yoshiro and Nakashima, Yoshikazu and Sato, Shuntaro and Shiraishi, Hirokazu and Nakamura, Tatsufumi and Fukuoka, Junya and Nakamura, Takashi and Kawakami, Atsushi},
 journal = {BMC Musculoskeletal Disorders},
 month = {Nov},
 note = {Background: The aim of the study was to reassess the prevalence and characteristics of human T lymphotropic virus type I (HTLV-I)-associated Sjogren's syndrome (SS) and SS in HTLV-I-associated myelopathy (HAM) based on the American European Consensus Group (AECG) criteria in HTLV-I endemic area, Nagasaki prefecture. Methods: The 349 patients who underwent a minor salivary gland biopsy (MSGB) for suspected SS were retrospectively classified by AECG classification criteria and divided with or without anti-HTLV-I antibody. Results: The HTLV-I data-available 294 patients were investigated. One hundred-seventy patients were classified as SS and 26.5 % were HTLV-I-seropositive. We have included 26 patients with HTLV-I-associated myelopathy (HAM) and 38.5 % were classified as having SS. The prevalences of ANA and anti-SS-A/Ro antibody of HAM + SS were significantly low compared to the HTLV-I asymptomatic carriers (AC) with SS and the HTLV-I-seronegative SS patients, although lacrimal dysfunction tended to be high in HAM + SS and significantly high in AC + SS patients compared with the patients with HTLV-I-seronegative SS. The focus scores of MSGB in the HAM + SS patients were similar to those of the AC + SS patients and the HTLV-I-seronegative patients with SS. Among the MSGB-positive patients, there was a low prevalence of ANA in the HAM + SS patients. Similar results were obtained in case of anti-SS-A/Ro or SS-B/La antibody. Conclusion: In HTLV-I endemic area, high prevalence of anti-HTLV-I antibody among SS as well as the characteristics of HAM + SS and AC + SS was still determined by AECG classification criteria., BMC Musculoskeletal Disorders, 16, 335; 2015},
 title = {Reevaluation for clinical manifestations of HTLV-I-seropositive patients with Sjogren’s syndrome},
 volume = {16},
 year = {2015}
}