{"created":"2023-05-15T16:32:58.378148+00:00","id":5025,"links":{},"metadata":{"_buckets":{"deposit":"543e52fa-67bb-4892-bac0-fdc7e1fb8b42"},"_deposit":{"created_by":2,"id":"5025","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"5025"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00005025","sets":["29:30:1713167819629:311"]},"author_link":["20671","20669","20663","20666","20672","20673","20670","20662","20668","20667","20664","20665"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"44","bibliographicPageStart":"39","bibliographicVolumeNumber":"60","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective: Cisplatin is well known for producing severe adverse events, including renal dysfunction. To prevent renal dysfunction\ncaused by cisplatin, routine magnesium supplementation is recommended. However, few reports exist about the efficacy of\nmagnesium in preventing renal dysfunction. Therefore, the purpose of this study was to retrospectively survey the efficacy of\nmagnesium in preventing renal dysfunction after administration of cisplatin.\nMethods: We evaluated patients who received first-line cisplatin-based chemotherapy from May 2008 to June 2013.\nResults: Data from 146 patients and a total of 394 treatments was analyzed. Elevation of serum creatinine was detected in 77 /\n394 treatments (19.5%). Statistical significance was found between prevention of elevation of serum creatinine and magnesium\nsupplementation. The other significant parameters were serum creatinine and eGFR levels before treatment and patient age. In\nmultivariate analysis, magnesium and eGFR before treatment were statistically significant.\nConclusions: The study results suggest that magnesium supplementation might reduce nephrotoxicity caused by cisplatin. The\neGFR level before treatment might be an important factor associated with nephrotoxicity after cisplatin administration.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia, 60(2), pp.39-44; 2016","subitem_description_type":"Other"}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagasaki University School of Medicine"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"2"}]},"item_3_text_63":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"長崎大学医学部"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Motoshima, Kohei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, Yoichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimada, Midori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitazaki, Takeshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Senju, Hiroaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ogawara, Daiki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takemoto, Shinnosuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mizoguchi, Kosuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sato, Shuntaro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakatomi, Katsumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukuda, Minoru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kohno, Shigeru"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"ActMed60_39.pdf","filesize":[{"value":"907.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ActMed60_39.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/5025/files/ActMed60_39.pdf"},"version_id":"079f8485-9093-411d-8709-297f47cb60d0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"cisplatin","subitem_subject_scheme":"Other"},{"subitem_subject":"renal dysfunction","subitem_subject_scheme":"Other"},{"subitem_subject":"magnesium","subitem_subject_scheme":"Other"},{"subitem_subject":"eGFR","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The efficacy of magnesium in preventing renal dysfunction due to high-dose cisplatin for treatment of thoracic tumor","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The efficacy of magnesium in preventing renal dysfunction due to high-dose cisplatin for treatment of thoracic tumor"}]},"item_type_id":"3","owner":"2","path":["311"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-02-09"},"publish_date":"2016-02-09","publish_status":"0","recid":"5025","relation_version_is_last":true,"title":["The efficacy of magnesium in preventing renal dysfunction due to high-dose cisplatin for treatment of thoracic tumor"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2024-04-16T05:28:10.749966+00:00"}