{"created":"2023-05-15T16:33:04.168607+00:00","id":5159,"links":{},"metadata":{"_buckets":{"deposit":"594e19e8-5466-45dc-bfbc-4d00abcf8c01"},"_deposit":{"created_by":2,"id":"5159","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"5159"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00005159","sets":["8:9"]},"author_link":["21387","21388","21391","21392","21394","21395","21396","21389","21386","21390","21393","21385"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-03","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"598","bibliographicPageStart":"594","bibliographicVolumeNumber":"7","bibliographic_titles":[{"bibliographic_title":"Experimental and Therapeutic Medicine"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Endoscopic submucosal dissection (ESD) enables the curative resection of early gastric cancer (EGC); however, little information is available on the long-term outcomes of ESD. This study was conducted to clarify the clinical outcomes of a large number of patients with EGC who underwent ESD. The early outcomes were assessed in 1,209 patients and the long-term outcomes were assessed in 300 patients at a follow-up >5 years after the ESD procedure. The overall survival rates were compared between indication and expanded-indication groups, and between the patients who did or did not undergo additional surgery in an out-of-indication group. Overall survival rates were also compared among different age groups. In total, 617 lesions were classed as the indication group, 507 as the expanded-indication group and 208 as the out-of-indication group. Curative resection rates were 96.6% and 91.5% in the indication and expanded-indication groups, respectively. In terms of the long-term outcomes, 20 of the 146 patients in the indication group, 15 of the 105 patients in the expanded-indication group and one of the 23 patients who underwent additional surgery in the out-of-indication group succumbed due to causes other than gastric cancer. Among the 26 patients who did not undergo additional surgery in the out-of-indication group, 10 mortalities occurred, including one due to gastric cancer. The five-year survival rates were not significantly different between the indication and expanded-indication groups. In the out-of-indication group, the five-year survival rate for the patients who did not undergo additional surgery (65.0%) was significantly lower than that for those who did undergo additional surgery (100%) (P<0.01). The five-year survival rate of patients aged >80 years (67.1%) was significantly lower than that of the younger patients (<60 years, 91.6%; sixties, 93.0%; seventies, 84.5%) (P<0.0001). In conclusion, although expanded-indication of ESD for EGC is appropriate, comorbidities require consideration in elderly patients.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Experimental and Therapeutic Medicine, 7(3), pp.594-598; 2014","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Spandidos Publications"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3892/etm.2014.1488","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c Spandidos Publications 2014. All rights reserved."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"17920981","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"17921015","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ohnita, Ken"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Isomoto, Hajime"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shikuwa, Saburo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yajima, Hiroyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Minami, Hitomi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsushima, Kayoko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Akazawa, Yuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamaguchi, Naoyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukuda, Eiichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nishiyama, Hitoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeshima, Fuminao"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakao, Kazuhiko"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"ETM7_594.pdf","filesize":[{"value":"317.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ETM7_594.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/5159/files/ETM7_594.pdf"},"version_id":"e7f29ed7-fccf-407d-a43a-546536facbb1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Early gastric cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"Early outcomes","subitem_subject_scheme":"Other"},{"subitem_subject":"Endoscopic submucosal dissection","subitem_subject_scheme":"Other"},{"subitem_subject":"Long-term outcomes","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Early and long?term outcomes of endoscopic submucosal dissection for early gastric cancer in a large patient series","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Early and long?term outcomes of endoscopic submucosal dissection for early gastric cancer in a large patient series"}]},"item_type_id":"2","owner":"2","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-10-01"},"publish_date":"2014-10-01","publish_status":"0","recid":"5159","relation_version_is_last":true,"title":["Early and long?term outcomes of endoscopic submucosal dissection for early gastric cancer in a large patient series"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:10:52.407179+00:00"}