{"created":"2023-05-15T16:33:13.370241+00:00","id":5371,"links":{},"metadata":{"_buckets":{"deposit":"cb98bd11-4e38-4eab-92a2-1c6b56a169bb"},"_deposit":{"created_by":2,"id":"5371","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"5371"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00005371","sets":["10:11"]},"author_link":["22695","22694","22692","22697","22690","22693","22689","22691","22698","22696"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-04-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"843","bibliographicPageStart":"837","bibliographicVolumeNumber":"53","bibliographic_titles":[{"bibliographic_title":"Internal Medicine"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objective Our previous study reported that categorizing diabetes patients according to the serum triglycerides-to-high-density lipoprotein cholesterol (TG-HDL) ratio is useful for estimating the risk of atherosclerosis, as a high TG-HDL ratio in patients with diabetes constitutes risk factors for atherosclerosis. Another study showed that a high hemoglobin level is associated with the risk of atherosclerosis. However, no previous studies have examined the association between the hemoglobin level and diabetes categorized by the TG-HDL ratio. In order to investigate these associations, we conducted a cross-sectional study of 3,733 (1,299 men and 2,434 women) Japanese participants 30-89 years of age undergoing a general health checkup. Methods We investigated the association between the hemoglobin levels and the incidence of diabetes in all subjects, who were divided into tertiles according to the TG-HDL ratio. Diabetes was defined as an HbA1c (NGSP) level of ?6.5% and/or the initiation of glucose-lowering or insulin therapy. Results Of the 265 diabetes patients identified in this study, 116 had a high TG-HDL ratio (high TG-HDL diabetes) and 71 had a low TG-HDL ratio (low TG-HDL diabetes). Independent from classical cardiovascular risk factors, the multivariate odds ratio of a 1 SD (standard deviation) increment in hemoglobin (1.30 g/dL for men, 1.16 g/dL for women) was 1.04 (95% confidence intervals (CI): 0.88-1.22) for all patients with diabetes, 1.44 (95%CI: 1.17-1.77) for the patients with high TG-HDL diabetes and 0.67 (95%CI: 0.54-0.83) for the patients with low TG-HDL diabetes. Conclusion The hemoglobin level is positively associated with high TG-HDL diabetes and inversely associated with low TG-HDL diabetes. These findings suggest that measuring the hemoglobin level is clinically relevant for estimating the risk of atherosclerosis in patients with diabetes categorized according to the TGHDL ratio.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Internal Medicine, 53(8), pp.837-843; 2014","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本内科学会"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.2169/internalmedicine.53.1423","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2014 The Japanese Society of Internal Medicine."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09182918","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13497235","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"Japanese Society of Internal Medicine"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shimizu, Yuji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakazato, Mio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sekita, Takaharu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Koyamatsu, Jun"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kadota, Koichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamasaki, Hironori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Goto, Hisashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takamura, Noboru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Aoyagi, Kiyoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Takahiro"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"IntMed53_837.pdf","filesize":[{"value":"148.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"IntMed53_837.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/5371/files/IntMed53_837.pdf"},"version_id":"24018211-3d3f-4581-8893-4c701fe462bc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Cross-sectional study","subitem_subject_scheme":"Other"},{"subitem_subject":"Diabetes","subitem_subject_scheme":"Other"},{"subitem_subject":"Hemoglobin","subitem_subject_scheme":"Other"},{"subitem_subject":"Japanese","subitem_subject_scheme":"Other"},{"subitem_subject":"TG-HDL","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Association between Hemoglobin and Diabetes in Relation to the Triglycerides-to-High-Density Lipoprotein Cholesterol (TG-HDL) Ratio in Japanese Individuals: The Nagasaki Islands Study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Association between Hemoglobin and Diabetes in Relation to the Triglycerides-to-High-Density Lipoprotein Cholesterol (TG-HDL) Ratio in Japanese Individuals: The Nagasaki Islands Study"}]},"item_type_id":"2","owner":"2","path":["11"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-06-05"},"publish_date":"2014-06-05","publish_status":"0","recid":"5371","relation_version_is_last":true,"title":["Association between Hemoglobin and Diabetes in Relation to the Triglycerides-to-High-Density Lipoprotein Cholesterol (TG-HDL) Ratio in Japanese Individuals: The Nagasaki Islands Study"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:06:12.514784+00:00"}