@article{oai:nagasaki-u.repo.nii.ac.jp:00005613,
 author = {Haraguchi, Wataru and Matsuo, Takayuki and Yoshida, Koichi and Nagata, Izumi},
 issue = {1},
 journal = {Acta medica Nagasakiensia},
 month = {Jul},
 note = {AUF1 is one of Adenine-and-Uridine-rich elements binding protein which regulates the mRNA stability of many genes related to growth regulation, cytokines, and cell cycle-regulatory genes. There was no report about the expression of AUF1 in gliomas. Sections of formalin-fixed, paraffin-embedded tissues from 71 gliomas were stained immunohistochemically using a polyclonal antibody against the adenine-and-uridine-rich element RNA-Binding factor 1 (AUF1) oncoprotein. Positive staining, which is known to correlate with gene amplification, was not associated with patients' sex, age, Karnofsky performance status scores (KPS), tumor size, Bcl-2 expression, or longer overall survival. However, positive staining was negatively correlated with the MIB-1 labeling index, while it was positively correlated with the lower grade group of WHO classification. Expression of the AUF1 oncoprotein appears to be an important additional indicator in human gliomas., Acta medica Nagasakiensia, 59(1), pp.7-11; 2014},
 pages = {7--11},
 title = {Adenine-and-Uridine-rich element RNA-binding factor 1 (AUF1) as an additional marker in human gliomas},
 volume = {59},
 year = {2014}
}