{"created":"2023-05-15T16:33:23.898404+00:00","id":5615,"links":{},"metadata":{"_buckets":{"deposit":"2c0958ef-fa98-4d3f-a765-1cc04f67f1b2"},"_deposit":{"created_by":2,"id":"5615","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"5615"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00005615","sets":["29:30:1713167819629:346"]},"author_link":["23803","23800","23801","23797","23802","23805","23799","23795","23804","23796","23798"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-07","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"25","bibliographicPageStart":"15","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objectives: Reactive oxygen species (ROS) function as key metabolites that can impair biological processes. The aim of this preliminary study was to assess the perioperative oxidative changes in lung cancer surgery.\nMethods: We measured the levels of blood hydroperoxides, a type of ROS, as an index of oxidative injury to cellular components, as well as the plasma ferric-reducing ability as an index of total antioxidant potential in 32 lung cancer patients. Hydroperoxides were measured by the levels of diacron reactive oxygen metabolites (d-ROMs). The antioxidant potential was determined by the biological antioxidant potential (BAP), which represents the levels of endogenous antioxidant enzymes.\nResults: Lung cancer patients had slightly affected oxidative stress before surgery. The d-ROM and BAP levels after surgery and were significantly decreased than before surgery (p< 0.001) and the levels recovered preoperatively at third postoperative day. The d-ROM level in video-assisted surgery group (n=17) was significantly decreased than those in thoracotomy group (n=15) at third and seventh post-operative day (p < 0.001, and < 0.02).\nConclusions: Lung cancer patients had already exposed oxidative stress before surgery and surgical intervention also generates large amounts of ROS. Video-assisted thoracic surgery can reduce the ROS compared to the standard thoractomy.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia, 59(1), pp.19-25; 2014","subitem_description_type":"Other"}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagasaki University School of Medicine"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"4"}]},"item_3_text_63":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"長崎大学医学部"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Miyazaki, Takuro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takagi, Katsunori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mine, Mariko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamasaki, Naoya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tsuchiya, Tomoshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsumoto, Keitaro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hatachi, Go"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Izumino, Hiroo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Doi, Ryoichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Machino, Ryusuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagayasu, Takeshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"ActMed59_19.pdf","filesize":[{"value":"627.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ActMed59_19.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/5615/files/ActMed59_19.pdf"},"version_id":"5925c9ac-9339-49e8-b5a2-349dc3742bca"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"lung cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"oxidative stress","subitem_subject_scheme":"Other"},{"subitem_subject":"video-assisted thoracic surgery","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Video-assisted thoracic surgery attenuates perioperative oxidative stress response in lung cancer patients: a preliminary study","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Video-assisted thoracic surgery attenuates perioperative oxidative stress response in lung cancer patients: a preliminary study"}]},"item_type_id":"3","owner":"2","path":["346"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-09-09"},"publish_date":"2014-09-09","publish_status":"0","recid":"5615","relation_version_is_last":true,"title":["Video-assisted thoracic surgery attenuates perioperative oxidative stress response in lung cancer patients: a preliminary study"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2024-04-16T05:29:09.019067+00:00"}