@article{oai:nagasaki-u.repo.nii.ac.jp:00005661, author = {Takaki, Masahiro and Nakama, Takahiro and Ishida, Masayuki and Morimoto, Hitomi and Nagasaki, Yuka and Shiramizu, Rina and Hamashige, Naohisa and Chikamori, Masayuki and Yoshida, Laymyint and Ariyoshi, Koya and Suzuki, Motoi and Morimoto, Konosuke}, issue = {4}, journal = {Japanese Journal of Infectious Diseases}, month = {Jul}, note = {The age-group-specific incidence and etiological patterns of community-acquired pneumonia (CAP) have not been fully established in Japan. A 2-year prospective surveillance was conducted in Kochi city, Western Japan. All CAP patients aged ?15 years who visited a community-based hospital were enrolled in the study. Clinical samples were examined by conventional bacterial culture and urinary antigen tests, and 6 bacterial pathogens and 16 respiratory viruses were identified from sputum samples by multiplex polymerase chain reaction assays. The age-group-specific incidence of CAP was estimated using a population-based data set of the total number of outpatients in the whole city. Ninety of the 131 enrolled patients, 68.7zwere positive for respiratory pathogens. Streptococcus pneumoniae was the leading bacterial pathogen identified (28.2z). Respiratory viruses were identified in 36 patients (27.5z), and human entero-rhinovirus was the most common (13.3z) among them. The estimated overall incidence of adult CAP in Kochi was 9.6 per 1,000 person-years (PY); the estimated age group-specific incidence was 3.4, 10.7, and 42.9 per 1,000 PY for those aged 15-64, 65-74, and ?75 years, respectively. The high incidence of CAP in these rural city of Japan, probably reflects the substantial aged population. S. pneumoniae and respiratory viruses play important roles in CAP in all age groups., Japanese Journal of Infectious Diseases, 67(4), pp.269-275; 2014}, pages = {269--275}, title = {High Incidence of Community-Acquired Pneumonia among Rapidly Aging Population in Japan: A Prospective Hospital-Based Surveillance}, volume = {67}, year = {2014} }