{"created":"2023-05-15T16:33:25.968492+00:00","id":5663,"links":{},"metadata":{"_buckets":{"deposit":"556cb52e-32cc-4dab-9029-c0d26355ecb5"},"_deposit":{"created_by":2,"id":"5663","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"5663"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00005663","sets":["73:74"]},"author_link":["24110","24108","24111","24109","24112","24107"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"688","bibliographicPageStart":"683","bibliographicVolumeNumber":"4","bibliographic_titles":[{"bibliographic_title":"FEBS Open Bio"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The influenza virus replicates in the host cell nucleus, and the progeny viral ribonucleoprotein complex (vRNP) is exported to the cytoplasm prior to maturation. NS2 has a nuclear export signal that mediates the nuclear export of vRNP by the vRNP-M1-NS2 complex. We previously reported that the heat shock cognate 70 (Hsc70) protein binds to M1 protein and mediates vRNP export. However, the interactions among M1, NS2, and Hsc70 are poorly understood. In the present study, we demonstrate that Hsc70 interacts with M1 more strongly than with NS2 and competes with NS2 for M1 binding, suggesting an important role of Hsc70 in the nuclear export of vRNP.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"FEBS Open Bio, 4, pp.683-688; 2014","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier BV"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.fob.2014.07.004","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"c 2014 The Authors. Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/)."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"22115463","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Watanabe, Ken"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimizu, Teppei"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Noda, Saiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tsukahara, Fujiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maru, Yoshiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kobayashi, Nobuyuki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"FEBSOB4_683.pdf","filesize":[{"value":"914.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"FEBSOB4_683.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/5663/files/FEBSOB4_683.pdf"},"version_id":"0b8bf378-cf0f-4c0d-844d-0e3caa9b36a7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Dissociation constant","subitem_subject_scheme":"Other"},{"subitem_subject":"Hsc70","subitem_subject_scheme":"Other"},{"subitem_subject":"Influenza virus","subitem_subject_scheme":"Other"},{"subitem_subject":"M1","subitem_subject_scheme":"Other"},{"subitem_subject":"NS2","subitem_subject_scheme":"Other"},{"subitem_subject":"Nuclear export","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2"}]},"item_type_id":"2","owner":"2","path":["74"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-10-03"},"publish_date":"2014-10-03","publish_status":"0","recid":"5663","relation_version_is_last":true,"title":["Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T03:01:18.926729+00:00"}