@article{oai:nagasaki-u.repo.nii.ac.jp:00005829,
 author = {Tateishi, Yohei and Tsujino, Akira and Hamabe, Jumpei and Tsuneto, Akira and Maemura, Koji and Tasaki, Osamu and Horie, Nobutaka and Izumo, Tsuyoshi and Hayashi, Kentaro and Nagata, Izumi},
 issue = {1-2},
 journal = {Journal of the Neurological Sciences},
 month = {Oct},
 note = {Background: The aim of this study was to identify whether diastolic dysfunction predicts in-hospital death in ischemic stroke patients with atrial fibrillation. Method: We retrospectively analyzed data fromenrolled patients with ischemic stroke patients with atrial fibrillation who presented within 24 h of onset. All patients underwent transthoracic echocardiography to evaluate diastolic filling pressure estimated as the ratio of early transmitral flow velocity (E) to mitral annular velocity (e')within 24 h of admission.Weevaluated initial ischemic lesion volume andNational Institute of Health Stroke Scale (NIHSS) score. Results: Two hundred and sixty-six patients were enrolled.During hospitalization, 30 patients (11%) died. The deceased group had a higher NIHSS score, a higher D-dimer level, a higher creatinine level, a larger initial ischemic lesion volumeand a higher E/e' ratio than those in the survival group. In amultivariate analysis, a higher E/e' ratio was an independent predictor of in-hospital death. The cutoff value for the E/e' ratio for prediction in-hospital death was 20 with the sensitivity of 75% and specificity of 86%. Conclusion: Diastolic dysfunction may be associatedwith in-hospital death in ischemic stroke patientswith atrial fibrillation., Journal of the Neurological Sciences, 345(1-2), pp.83-86; 2014},
 pages = {83--86},
 title = {Cardiac diastolic dysfunction predicts in-hospital mortality in acute ischemic stroke with atrial fibrillation},
 volume = {345},
 year = {2014}
}