{"created":"2023-05-15T16:33:35.848384+00:00","id":5890,"links":{},"metadata":{"_buckets":{"deposit":"2e8df860-c856-4e5f-88ad-3e31ddc6c9e2"},"_deposit":{"created_by":2,"id":"5890","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"5890"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00005890","sets":["29:30:1713167819629:358"]},"author_link":["25390","25400","25395","25394","25396","25398","25399","25392","25391","25389","25393","25397"],"item_3_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"71","bibliographicPageStart":"67","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"Acta medica Nagasakiensia"}]}]},"item_3_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction\n　Gefitinib is a molecularly targeted drug for oral administration, a selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). It is effective for patients with lung cancer who have EGFR mutation and enables long-term survival of patients with advanced disease.\nCase presentation\n　An 84-year-old Asian female with lung cancer (adenocarcinoma, cT4N3M1b stage IV PUL BRA OSS ADR) was treated by gefitinib for two years. The primary tumor was markedly reduced, and bone metastasis had almost disappeared. However, the patient became unconsciousness with general edema and died two days after falling unconsciousness. In the autopsy, it was diagnosed as infectious cerebral thromboembolism due to infectious endocarditis. The cause of death was cardiac tamponade.\nConclusions\n　While long-term survival can be expected in patients with advanced lung cancer by molecular-targeted agents, cautious management is warranted for complications, the same as for the primary disease.","subitem_description_type":"Abstract"}]},"item_3_description_64":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Acta medica Nagasakiensia, 59(2), pp.67-71; 2014","subitem_description_type":"Other"}]},"item_3_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Nagasaki University School of Medicine"}]},"item_3_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00508430","subitem_source_identifier_type":"NCID"}]},"item_3_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00016055","subitem_source_identifier_type":"ISSN"}]},"item_3_text_62":{"attribute_name":"sortkey","attribute_value_mlt":[{"subitem_text_value":"5"}]},"item_3_text_63":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"長崎大学医学部"}]},"item_3_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shimada, Midori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukuda, Minoru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Onn, Yumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Abe, Noriko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Irie, Junji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kitazaki, Takeshi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hashiguchi, Kohji"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fukuda, Masaaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakamura, Yoichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Suyama, Naofumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ashizawa, Kazuto"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kohno, Shigeru"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"ActMed59_67.pdf","filesize":[{"value":"686.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ActMed59_67.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/5890/files/ActMed59_67.pdf"},"version_id":"f850126d-9869-46fa-aedb-da774d28cf7d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"lung cancer","subitem_subject_scheme":"Other"},{"subitem_subject":"infectious endocarditis","subitem_subject_scheme":"Other"},{"subitem_subject":"gefitinib","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Infectious cerebral thromboembolism in a patient with lung cancer during long-term administration of gefitinib: a case report","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Infectious cerebral thromboembolism in a patient with lung cancer during long-term administration of gefitinib: a case report"}]},"item_type_id":"3","owner":"2","path":["358"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-12-26"},"publish_date":"2014-12-26","publish_status":"0","recid":"5890","relation_version_is_last":true,"title":["Infectious cerebral thromboembolism in a patient with lung cancer during long-term administration of gefitinib: a case report"],"weko_creator_id":"2","weko_shared_id":2},"updated":"2024-04-16T05:28:44.315822+00:00"}