@article{oai:nagasaki-u.repo.nii.ac.jp:00006005,
 author = {Abo, Takafumi and Nanashima, Atsushi and Tobinaga, Syuuichi and Hidaka, Shigekazu and Taura, Naota and Takagi, Katsunori and Arai, Junichi and Miyaaki, Hisamitsu and Shibata, Hidetaka and Nagayasu, Takeshi},
 issue = {2},
 journal = {European Journal of Surgical Oncology (EJSO)},
 month = {Feb},
 note = {Background To improve the diagnostic accuracy for hepatic tumors on the liver surface, we investigated the usefulness of an indocyanine green-photodynamic eye (ICG-PDE) system by comparison with Sonazoid intraoperative ultrasonography (IOUS) in 117 patients. Hepatic segmentation by ICG-PDE was also evaluated. Methods ICG was administered preoperatively for functional testing and images of the tumor were observed during hepatectomy using a PDE camera. ICG was injected into portal veins to determine hepatic segmentation. Results Accurate diagnosis of liver tumors was achieved with ICG-PDE in 75% of patients, lower than with IOUS (94%). False-positive and false-negative diagnosis rates for ICG-PDE were 24% and 9%, respectively. New small HCCs were detected in 3 patients. The ICG fluorescent pattern in tumors was strong staining in 41%, weak staining in 13%, rim staining in 20% and no staining in 26%. Hepatocellular carcinoma predominantly showed strong staining (61%), while rim staining predominated in cholangiocellular carcinoma (60%) and liver metastasis (55%). Hepatic segmental staining was performed in 28 patients, proving successful in 89%. Conclusion ICG-PDE is a useful tool for detecting the precise tumor location at the liver surface, identifying new small tumors, and determining liver segmentation for liver resection., European Journal of Surgical Oncology (EJSO), 41(2), pp.257-264; 2015},
 pages = {257--264},
 title = {Usefulness of intraoperative diagnosis of hepatic tumors located at the liver surface and hepatic segmental visualization using indocyanine green-photodynamic eye imaging},
 volume = {41},
 year = {2015}
}