{"created":"2023-05-15T16:33:46.224638+00:00","id":6134,"links":{},"metadata":{"_buckets":{"deposit":"da1d43a1-95ac-4f75-81f7-edceadb84b26"},"_deposit":{"created_by":2,"id":"6134","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"6134"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00006134","sets":["50:51"]},"author_link":["26656","26652","26657","26653","26655","26654"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-08","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"312","bibliographicPageStart":"305","bibliographicVolumeNumber":"59","bibliographic_titles":[{"bibliographic_title":"International Journal of Biological Macromolecules"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Antioxidant activities of sulfated polysaccharide ascophyllan from Ascophyllum nodosum was investigated in vitro by various assays, and compared with those of fucoidan. A chemiluminescence (CL) analysis using a luminol analog, L-012, showed that ascophyllan scavenges superoxide, and the activity is greater than fucoidan. However, in the presence of 10μg/ml of ascophyllan or 10μg/ml and 100μg/ml of fucoidan, slightly enhanced CL-responses were observed. Since EDTA-treatment resulted in disappearance of the enhancement effects, it was suggested that metal ions especially iron ions in the polysaccharides might be involved in this phenomenon. In fact, metal element analysis revealed that ascophyllan and fucoidan inherently contain iron and other metal elements. EDTA-treatment resulted in significant increase in Fe2+-chelating activities of these polysaccharides. In an electron spin resonance (ESR)-spin trapping analysis in which direct UV-radiation to hydrogen peroxide was used as a source of hydroxyl radical, ascophyllan and fucoidan showed potent hydroxyl radical scavenging activity with similar extent. Reducing power of ascophyllan was stronger than that of fucoidan. Our results indicate that ascophyllan can exhibit direct and potent antioxidant activity.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"International Journal of Biological Macromolecules, 59, pp.305-312; 2013","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.ijbiomac.2013.04.035","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 Elsevier B.V."},{"subitem_rights":"NOTICE: this is the author’s version of a work that was accepted for publication in International Journal of Biological Macromolecules. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in International Journal of Biological Macromolecules, 59(2013)"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"01418130","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Abu, Ryogo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Jiang, Zedong"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ueno, Mikinori"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Okimura, Takasi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamaguchi, Kenichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Oda, Tatsuya"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"IJBM59_305.pdf","filesize":[{"value":"506.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"IJBM59_305.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/6134/files/IJBM59_305.pdf"},"version_id":"b39e464b-61a6-4d2c-8ce3-0ba4f592303d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Antioxidant activities","subitem_subject_scheme":"Other"},{"subitem_subject":"Ascophyllan","subitem_subject_scheme":"Other"},{"subitem_subject":"Fucoidan","subitem_subject_scheme":"Other"},{"subitem_subject":"Hydroxyl radical scavenging activity","subitem_subject_scheme":"Other"},{"subitem_subject":"Reducing power","subitem_subject_scheme":"Other"},{"subitem_subject":"Superoxide scavenging activity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"In vitro antioxidant activities of sulfated polysaccharide ascophyllan isolated from Ascophyllum nodosum","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"In vitro antioxidant activities of sulfated polysaccharide ascophyllan isolated from Ascophyllum nodosum"}]},"item_type_id":"2","owner":"2","path":["51"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-07-31"},"publish_date":"2013-07-31","publish_status":"0","recid":"6134","relation_version_is_last":true,"title":["In vitro antioxidant activities of sulfated polysaccharide ascophyllan isolated from Ascophyllum nodosum"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:51:24.790116+00:00"}