{"created":"2023-05-15T16:33:59.923121+00:00","id":6440,"links":{},"metadata":{"_buckets":{"deposit":"80800b93-76e1-463b-a45c-32d78f52c147"},"_deposit":{"created_by":2,"id":"6440","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"6440"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00006440","sets":["50:51"]},"author_link":["27409","27415","27416","27410","27414","27411","27412","27413"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-09-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"133","bibliographicPageStart":"128","bibliographicVolumeNumber":"71","bibliographic_titles":[{"bibliographic_title":"Toxicon"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"To reveal the accumulation profile of tetrodotoxin (TTX) in pufferfish Takifugu rubripes juveniles, we compared the localization of TTX in various tissues among wild juveniles and hatchery-reared juveniles with or without TTX administration using immunohistochemical technique with anti-TTX monoclonal antibody. Immuno-positive reaction was observed in hepatic tissue, basal cell of skin and olfactory, olfactory epithelium, optic nerve and brain (optic tectum, cerebellum, medulla oblongata) of wild juveniles (body length: BL, 4.7-9.4cm). TTX was detected in the same tissues as wild juveniles and epithelial cell layer of intestine of hatchery-reared juveniles (BL, 5.0-5.3cm) to which TTX was orally administrated. No positive reaction was observed from the tissues of hatchery-reared juveniles without TTX administration. These results suggest that orally administrated TTX to the non-toxic cultured juveniles is accumulated in the same manner of wild juveniles. In addition, our study revealed that pufferfish accumulates TTX in the central nervous system.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Toxicon, 71, pp.128-133; 2013","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier Limited"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.toxicon.2013.05.018","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 Elsevier Ltd."},{"subitem_rights":"NOTICE: this is the author’s version of a work that was accepted for publication in Toxicon. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Toxicon, 71(2013)"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00410101","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Okita, Kogen"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takatani, Tomohiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakayasu, Junichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamazaki, Hideki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakiyama, Kazutaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikeda, Koichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Arakawa, Osamu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakakura, Yoshitaka"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"Toxicon71_128.pdf","filesize":[{"value":"3.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Toxicon71_128.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/6440/files/Toxicon71_128.pdf"},"version_id":"8368a9fe-c965-40a8-b0f2-6058ebf29beb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Central nervous system","subitem_subject_scheme":"Other"},{"subitem_subject":"Immunohistochemistry","subitem_subject_scheme":"Other"},{"subitem_subject":"Pufferfish","subitem_subject_scheme":"Other"},{"subitem_subject":"Takifugu rublipes","subitem_subject_scheme":"Other"},{"subitem_subject":"Tetrodotoxin (TTX)","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Comparison of the localization of tetrodotoxin between wild pufferfish Takifugu rubripes juveniles and hatchery-reared juveniles with tetrodotoxin administration","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Comparison of the localization of tetrodotoxin between wild pufferfish Takifugu rubripes juveniles and hatchery-reared juveniles with tetrodotoxin administration"}]},"item_type_id":"2","owner":"2","path":["51"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-08-22"},"publish_date":"2013-08-22","publish_status":"0","recid":"6440","relation_version_is_last":true,"title":["Comparison of the localization of tetrodotoxin between wild pufferfish Takifugu rubripes juveniles and hatchery-reared juveniles with tetrodotoxin administration"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:45:27.687727+00:00"}