{"created":"2023-05-15T16:34:09.351476+00:00","id":6657,"links":{},"metadata":{"_buckets":{"deposit":"c34fd586-90f0-4ef1-976b-ad341186341d"},"_deposit":{"created_by":2,"id":"6657","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"6657"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00006657","sets":["73:74"]},"author_link":["28047"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-07-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"1051","bibliographicPageStart":"1045","bibliographicVolumeNumber":"36","bibliographic_titles":[{"bibliographic_title":"Biological and Pharmaceutical Bulletin"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Polymeric micelles, which are formed by the self-assembly of block copolymers, can load various substances and have received attention as drug carriers. Negatively charged nucleic acids such as DNA or RNA are some of the drugs delivered by polyion complex-based polymeric micelles (polyplex micelles). Polyplex micelles are expected to be nonviral gene carriers instead of viral vectors, which have several problems including safety, the limited size of the loading gene, and productivity. In this review, recent studies by our group on smart polyplex micelles delivering genes will be introduced.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Biological and Pharmaceutical Bulletin, 36(7), pp.1045-1051; 2013","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本薬学会"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1248/bpb.b13-00287","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 The Pharmaceutical Society of Japan"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09186158","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"13475215","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"Pharmaceutical Society of Japan"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Oba, Makoto"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"BPBul36_1045.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"BPBul36_1045.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/6657/files/BPBul36_1045.pdf"},"version_id":"b303de83-d56f-47d7-a771-4775e68c7775"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Block copolymer","subitem_subject_scheme":"Other"},{"subitem_subject":"Gene carrier","subitem_subject_scheme":"Other"},{"subitem_subject":"Gene delivery system","subitem_subject_scheme":"Other"},{"subitem_subject":"Gene therapy","subitem_subject_scheme":"Other"},{"subitem_subject":"Polymeric micelle","subitem_subject_scheme":"Other"},{"subitem_subject":"Polyplex micelle","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Study on Development of Polymeric Micellar Gene Carrier and Evaluation of Its Functionality","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Study on Development of Polymeric Micellar Gene Carrier and Evaluation of Its Functionality"}]},"item_type_id":"2","owner":"2","path":["74"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-09-12"},"publish_date":"2013-09-12","publish_status":"0","recid":"6657","relation_version_is_last":true,"title":["Study on Development of Polymeric Micellar Gene Carrier and Evaluation of Its Functionality"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:40:30.311170+00:00"}