@article{oai:nagasaki-u.repo.nii.ac.jp:00006859, author = {Tsuchiya, Naho and Pathipvanich, Panita and Rojanawiwat, Archawin and Wichukchinda, Nuanjun and Koga, Ichiro and Koga, M. and Auwanit, Wattana and Kilgore, Paul Evan and Ariyoshi, Koya and Sawanpanyalert, Pathom}, issue = {9}, journal = {Epidemiology and Infection}, month = {Sep}, note = {A total of 755 highly active antiretroviral therapy (HAART)-naive HIV-infected patients were enrolled at a government hospital in Thailand from 1 June 2000 to 15 October 2002. Census date of survival was on 31 October 2004 or the date of HAART initiation. Of 700 (92·6%) patients with complete data, the prevalence of hepatitis B virus (HBV) surface antigen and anti-hepatitis C virus (HCV) antibody positivity was 11·9% and 3·3%, respectively. Eight (9·6%) HBV co-infected patients did not have anti-HBV core antibody (anti-HBcAb). During 1166·7 person-years of observation (pyo), 258 (36·9%) patients died [22·1/100 pyo, 95% confidence interval (CI) 16·7-27·8]. HBV and probably HCV co-infection was associated with a higher mortality with adjusted hazard ratios (aHRs) of 1·81 (95% CI 1·30-2·53) and 1·90 (95% CI 0·98-3·69), respectively. Interestingly, HBV co-infection without anti-HBc Ab was strongly associated with death (aHR 6·34, 95% CI 3·99-10·3). The influence of hepatitis co-infection on the natural history of HAART-naive HIV patients requires greater attention., Epidemiology and Infection, 141(9), pp.1840-1848; 2013}, pages = {1840--1848}, title = {Chronic hepatitis B and C co-infection increased all-cause mortality in HAART-naive HIV patients in northern Thailand}, volume = {141}, year = {2013} }