{"created":"2023-05-15T16:34:20.958047+00:00","id":6916,"links":{},"metadata":{"_buckets":{"deposit":"5b715d83-8476-458a-a3a0-4ed9a1e7dfc3"},"_deposit":{"created_by":2,"id":"6916","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"6916"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00006916","sets":["73:74"]},"author_link":["29036","29041","29042","29039","29037","29043","29040","29038"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-01-25","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"173","bibliographicPageStart":"170","bibliographicVolumeNumber":"88","bibliographic_titles":[{"bibliographic_title":"Journal of Pharmaceutical and Biomedical Analysis"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A simple and selective HPLC-fluorescence (FL) method with FL probe, 4-[4-(4-dimethylaminophenyl)-5-phenyl-1. H-imidazol-2-yl]benzoic acid methyl ester (DAPIM), for simultaneous determination of mercaptalbumin (HMA) and nonmercaptalbumin (HNA1) was developed. After HMA and HNA1 were separated on an ion-exchange column, they were on-line and post-column mixed with DAPIM. The DAPIM-albumin complex produces FL (λex 370. nm and λem 510. nm); however, DAPIM solution never gives the FL. Based on this mechanism, selective determination of HMA and HNA1 were achieved without any pretreatment and interfering peak. The proposed method was applied to the measurement of HMA and HNA1 in human serum of healthy volunteers and diabetes mellitus patients.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Journal of Pharmaceutical and Biomedical Analysis, 88, pp.170-173; 2014","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.jpba.2013.08.009","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 Elsevier B.V."}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"07317085","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ohyama, Kaname"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kishikawa, Naoya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuo, Aya"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Imazato, Takahiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ueki, Yukitaka"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Wada, Mitsuhiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nakashima, Kenichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kuroda, Naotaka"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"JPBA88_170.pdf","filesize":[{"value":"883.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JPBA88_170.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/6916/files/JPBA88_170.pdf"},"version_id":"8de0445c-72b8-44e7-aafe-132bb7daa066"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"4-[4-(4-dimethylaminophenyl)-5-phenyl-1H-imidazol-2-yl]Benzoic acid methyl ester","subitem_subject_scheme":"Other"},{"subitem_subject":"Fluorescence probe","subitem_subject_scheme":"Other"},{"subitem_subject":"Mercaptalbumin","subitem_subject_scheme":"Other"},{"subitem_subject":"Nonmercaptalbumin","subitem_subject_scheme":"Other"},{"subitem_subject":"Redox state","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Determination of the ratio between mercaptalbumin and nonmercaptalbumin by HPLC with fluorescence probe specifically binding to albumin","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Determination of the ratio between mercaptalbumin and nonmercaptalbumin by HPLC with fluorescence probe specifically binding to albumin"}]},"item_type_id":"2","owner":"2","path":["74"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-11-05"},"publish_date":"2013-11-05","publish_status":"0","recid":"6916","relation_version_is_last":true,"title":["Determination of the ratio between mercaptalbumin and nonmercaptalbumin by HPLC with fluorescence probe specifically binding to albumin"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:36:03.775381+00:00"}