{"created":"2023-05-15T16:34:23.912591+00:00","id":6980,"links":{},"metadata":{"_buckets":{"deposit":"9dc32231-aafc-4024-9a11-2849051009d7"},"_deposit":{"created_by":2,"id":"6980","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"6980"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00006980","sets":["29:30"]},"author_link":["29482","29484","29483","29481","29480","29479"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-11","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"135","bibliographicPageStart":"127","bibliographicVolumeNumber":"185","bibliographic_titles":[{"bibliographic_title":"Journal of Surgical Research"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background: Posthepatectomy complications have markedly decreased with advances in techniques and management; however, surgical risk to patients with injured livers is still not negligible. We evaluated several preoperative parameters of functional liver reserve tests in patients with various liver diseases as predictors of posthepatectomy complications. A comprehensive evaluation of preoperative liver functions is necessary for the prediction of the risk of posthepatectomy complications. Methods: Over a 10-y period, we examined 442 patients who underwent hepatectomy for liver and biliary diseases. The patients' background liver diseases included chronic viral liver diseases in 211 patients, obstructive jaundice in 29 patients, and normal liver in 202 patients. Hepatectomy-related postoperative complications (i.e., long-term ascites, intra-abdominal infection, and hepatic failure) occurred in 115 (26%) patients. A multivariate logistic analysis was performed to detect the predictive parameters, and a multivariate linear regression analysis was performed to derive a predictive formula for complications. Results: A univariate analysis identified 15 significant parameters associated with hepatectomy-related complications, and eight parameters (i.e., presence of chronic hepatic injury, clearance index by technetium-99 m galactosyl human serum albumin liver scintigraphy of ≥0.60, total bilirubin level of >1 mg/dL, serum hyaluronic acid level of ≥75 ng/mL, major hepatectomy, blood loss of ≥950 mL, operating time of ≥500 min, and combined resection of another organ or major vessel) were independent predictive factors identified in the multivariate analysis. Clearance index by technetium-99 m galactosyl human serum albumin liver, bilirubin level, hyaluronic acid level, and major hepatectomy were the parameters included in the predictive formula. Conclusions: In the present study, we present a comprehensive formula based on the predictive parameters for hepatic complications for prospective assessment to avoid posthepatectomy morbidity.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Journal of Surgical Research, 185(1), pp.127-135; 2013","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Academic Press Inc."}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.jss.2013.05.021","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 Elsevier Inc. All rights reserved."},{"subitem_rights":"NOTICE: this is the author’s version of a work that was accepted for publication in Journal of Surgical Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Surgical Research, 185, 1(2013)"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"00224804","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Nanashima, Atsushi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Abo, Takafumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Arai, Junichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsumoto, Hirofumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kudo, Takashi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nagayasu, Takeshi"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"JSR185_127.pdf","filesize":[{"value":"270.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"JSR185_127.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/6980/files/JSR185_127.pdf"},"version_id":"b34dcdbc-aa5a-4da0-bdb5-a14376d80f92"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"99mTc-GSA liver scintigraphy","subitem_subject_scheme":"Other"},{"subitem_subject":"Liver resection","subitem_subject_scheme":"Other"},{"subitem_subject":"Posthepatectomy complications","subitem_subject_scheme":"Other"},{"subitem_subject":"Prognostic functional parameters","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Functional liver reserve parameters predictive for posthepatectomy complications","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Functional liver reserve parameters predictive for posthepatectomy complications"}]},"item_type_id":"2","owner":"2","path":["30"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-12-13"},"publish_date":"2013-12-13","publish_status":"0","recid":"6980","relation_version_is_last":true,"title":["Functional liver reserve parameters predictive for posthepatectomy complications"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:34:30.692231+00:00"}