@article{oai:nagasaki-u.repo.nii.ac.jp:00007012, author = {Kakugawa, Tomoyuki and Tomimura, Saori and Hayashi, Tomayoshi and Sakamoto, Noriho and Ishimatsu, Yuji and Mukae, Hiroshi and Kohno, Shigeru}, issue = {4}, journal = {Respiration}, month = {Oct}, note = {A 76-year-old man with interstitial lung disease was admitted to our institution after developing persistent dyspnea upon effort. He also had a relapse of bullous eruptions on the skin of the trunk and extremities, previously diagnosed as vesicular pemphigoid. Direct immunofluorescence of a skin biopsy specimen using fluorescence microscopy showed the linear deposition of immunglobulin A (IgA), IgG and C3 along the basement membrane. These findings indicated a definitive diagnosis of linear IgA/IgG bullous dermatosis. Chest computed tomography, bronchoalveolar lavage and transbronchial lung biopsy findings suggested nonspecific interstitial pneumonia. Direct immunofluorescence of the lung biopsy specimens using fluorescence microscopy also showed a deposition of IgA, IgG and C3 along the epithelial cell membranes and basement membranes of the bronchioles and alveoli. Lung disorders associated with linear IgA/IgG bullous dermatosis are extremely rare and, to our knowledge, this is the first report of such a case of interstitial pneumonia., 著者版でのFigure 1は非公開。出版社版はDOIリンクを参照のこと。, Respiration, 86(4), pp.347-351; 2013}, pages = {347--351}, title = {Interstitial Pneumonia Associated with Linear Immunoglobulin A/Immunoglobulin G Bullous Dermatosis}, volume = {86}, year = {2013} }