{"created":"2023-05-15T16:34:28.563385+00:00","id":7088,"links":{},"metadata":{"_buckets":{"deposit":"902589ff-f810-43b3-bd8b-ac89dad82d19"},"_deposit":{"created_by":2,"id":"7088","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"7088"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00007088","sets":["73:74"]},"author_link":["29981","29983","29982","29980"],"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-02-26","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"4612","bibliographicPageStart":"4596","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"International Journal of Molecular Sciences"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"It has generally been considered that protein phosphatases have more diverse catalytic domain structures and mechanisms than protein kinases; however, gene annotation efforts following the human genome project appeared to have completed the whole array of protein phosphatases. Ser/Thr phosphatases are divided into three subfamilies that have different structures from each other, whereas Tyr phosphatases and dual-specificity phosphatases targeting Tyr, Ser and Thr belong to a single large family based on their common structural features. Several years of research have revealed, however, the existence of unexpected proteins, designated here as \"atypical protein phosphatases\", that have structural and enzymatic features different from those of the known protein phosphatases and are involved in important biological processes. In this review, we focus on the identification and functional characterization of atypical protein phosphatases, represented by eyes absent (EYA), suppressor of T-cell receptor signaling (Sts) and phosphoglycerate mutase family member 5 (PGAM5) and discuss their biological significance in cellular signaling.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"International Journal of Molecular Sciences, 14(3), pp.4596-4612; 2013","subitem_description_type":"Other"}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Multidisciplinary Digital Publishing Institute"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3390/ijms14034596","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/)."}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"14220067","subitem_source_identifier_type":"ISSN"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sadatomi, Daichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tanimura, Susumu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ozaki, Kei-ichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takeda, Kohsuke"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"IJMS14_4596.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"IJMS14_4596.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/7088/files/IJMS14_4596.pdf"},"version_id":"27350b4b-9f0f-4454-be59-bfc2d699f272"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"EYA","subitem_subject_scheme":"Other"},{"subitem_subject":"Mitochondria","subitem_subject_scheme":"Other"},{"subitem_subject":"PGAM5","subitem_subject_scheme":"Other"},{"subitem_subject":"Protein phosphatase","subitem_subject_scheme":"Other"},{"subitem_subject":"Sts","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Atypical Protein Phosphatases: Emerging Players in Cellular Signaling","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Atypical Protein Phosphatases: Emerging Players in Cellular Signaling"}]},"item_type_id":"2","owner":"2","path":["74"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-05-22"},"publish_date":"2013-05-22","publish_status":"0","recid":"7088","relation_version_is_last":true,"title":["Atypical Protein Phosphatases: Emerging Players in Cellular Signaling"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:32:13.760577+00:00"}