{"created":"2023-05-15T16:35:05.110613+00:00","id":7938,"links":{},"metadata":{"_buckets":{"deposit":"22a9de78-52e6-44fc-b6ad-81c1f0de69c9"},"_deposit":{"created_by":2,"id":"7938","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"7938"},"status":"published"},"_oai":{"id":"oai:nagasaki-u.repo.nii.ac.jp:00007938","sets":["50:51"]},"author_link":["32749","32746","32743","32745","32740","32738","32739","32748","32742","32747","32744","32741"],"item_2_alternative_title_19":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Protective Efficacy of a Commercial β-hemolytic Streptococcus Vaccine for Japanese Flounder against Streptococcus iniae Infection of Threadsail Filefish"}]},"item_2_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-03-22","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"31","bibliographicPageStart":"29","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"Fish Pathology"}]}]},"item_2_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"市販ヒラメ用β溶血性レンサ球菌症ワクチンがカワハギのS. iniae感染症に有効か否かを検討した。まず，攻撃方法を決定するためにカワハギ由来のS. iniaeを用いて人為感染試験を行った。その結果，筋肉接種法では 102 CFU/100 g 魚体重の攻撃菌数で死亡率は90％となった。一方，浸漬法では攻撃菌数108 CFU/mL，浸漬時間30分間でも死亡率は60％にとどまった。ワクチンの有効性試験では常用量およびその 1/10 量による免疫で有効性が確認された。常用量で免疫し，2 週間，1 か月，3 か月および 7 か月後に攻撃試験を行って予防効果を調べたところ，どの時点でも有効率（RPS）は80％以上であった。以上の結果から，ヒラメβ溶血性レンサ球菌症不活化ワクチンはカワハギのS. iniae感染症に有効であり，免疫効果が長期間持続することが示された。","subitem_description_type":"Abstract"},{"subitem_description":"A commercial β-hemolytic Streptococcus vaccine for Japanese flounder was examined for the protective efficacy against Streptococcus iniae infection of threadsail filefish Stephanolepis cirrhifer. In the artificial infection test a high mortality rate (90%) was obtained by intramuscular inoculation with S. iniae as low as 102 CFU/100 g body weight. In the vaccination test intraperitoneal inoculation with the vaccine at the usual and 1/10 dosages resulted in a high protective effect (RPS≥85%), and the high protective efficacy was kept for at least 7 months.","subitem_description_type":"Abstract"}]},"item_2_description_63":{"attribute_name":"引用","attribute_value_mlt":[{"subitem_description":"Fish Pathology, 48(1), pp.29-31; 2013","subitem_description_type":"Other"}]},"item_2_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"32744","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ishi, Yuji"}]},{"nameIdentifiers":[{"nameIdentifier":"32745","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yamada, Toshiyuki"}]},{"nameIdentifiers":[{"nameIdentifier":"32746","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sugihara, Yukitaka"}]},{"nameIdentifiers":[{"nameIdentifier":"32747","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Takami, Ikuo"}]},{"nameIdentifiers":[{"nameIdentifier":"32748","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Suga, Koushirou"}]},{"nameIdentifiers":[{"nameIdentifier":"32749","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kanai, Kinya"}]}]},"item_2_publisher_33":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本魚病学会"}]},"item_2_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.3147/jsfp.48.29","subitem_relation_type_select":"DOI"}}]},"item_2_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2013 日本魚病学会"}]},"item_2_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0388788X","subitem_source_identifier_type":"ISSN"}]},"item_2_source_id_8":{"attribute_name":"EISSN","attribute_value_mlt":[{"subitem_source_identifier":"18817335","subitem_source_identifier_type":"ISSN"}]},"item_2_text_62":{"attribute_name":"出版者別言語","attribute_value_mlt":[{"subitem_text_value":"Japanese Society of Fish Pathology"}]},"item_2_version_type_16":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"石井, 佑治"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"山田, 敏之"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"杉原, 志貴"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"高見, 生雄"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"菅, 向志郎"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"金井, 欣也"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"FisPat48_29.pdf","filesize":[{"value":"801.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"FisPat48_29.pdf","url":"https://nagasaki-u.repo.nii.ac.jp/record/7938/files/FisPat48_29.pdf"},"version_id":"bb21751b-e80f-4318-8761-c77d89989879"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Stephanolepis cirrhifer","subitem_subject_scheme":"Other"},{"subitem_subject":"threadsail filefish","subitem_subject_scheme":"Other"},{"subitem_subject":"Streptococcus iniae","subitem_subject_scheme":"Other"},{"subitem_subject":"vaccine","subitem_subject_scheme":"Other"},{"subitem_subject":"efficacy","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"カワハギのβ溶血性レンサ球菌症に対する市販ヒラメ用ワクチンの有効性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"カワハギのβ溶血性レンサ球菌症に対する市販ヒラメ用ワクチンの有効性"}]},"item_type_id":"2","owner":"2","path":["51"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-03-23"},"publish_date":"2014-03-23","publish_status":"0","recid":"7938","relation_version_is_last":true,"title":["カワハギのβ溶血性レンサ球菌症に対する市販ヒラメ用ワクチンの有効性"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-16T02:15:34.461492+00:00"}